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C-Peptide

The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.
Also Known As:
C-Peptide, Proinsulin; Connecting Peptide; C Peptide; C Peptide, Proinsulin; Proinsulin C Peptide; Proinsulin C-Peptide
Networked: 4672 relevant articles (234 outcomes, 588 trials/studies)

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Experts

1. Mari, Andrea: 29 articles (01/2022 - 12/2002)
2. Sima, Anders A F: 26 articles (04/2012 - 10/2002)
3. Greenbaum, Carla J: 24 articles (01/2020 - 01/2004)
4. Ludvigsson, Johnny: 23 articles (01/2022 - 11/2006)
5. Wahren, John: 22 articles (04/2016 - 08/2002)
6. McDonald, Timothy J: 21 articles (01/2022 - 02/2011)
7. Pacini, Giovanni: 21 articles (01/2022 - 05/2006)
8. Pollak, Michael N: 21 articles (01/2022 - 04/2005)
9. Herold, Kevan C: 21 articles (01/2021 - 01/2004)
10. Giovannucci, Edward L: 20 articles (01/2022 - 08/2007)

Related Diseases

1. Type 1 Diabetes Mellitus (Autoimmune Diabetes)
2. Insulin Resistance
3. Type 2 Diabetes Mellitus (MODY)
4. Body Weight (Weight, Body)
5. Hyperglycemia

Related Drugs and Biologics

1. Insulin (Novolin)
2. Glucose (Dextrose)
3. Glucagon (Glukagon)
4. Blood Glucose (Blood Sugar)
5. Glycated Hemoglobin (Glycosylated Hemoglobin)
6. Proinsulin
7. Albumins
8. Triglycerides (Triacylglycerol)
9. Creatinine
10. Adiponectin

Related Therapies and Procedures

1. Therapeutics
2. Glycemic Control
3. Bariatric Surgery
4. Transplantation
5. Gastric Bypass (Roux-en-Y Gastric Bypass)