Abstract | PURPOSE OF REVIEW: RECENT FINDINGS: Molecular mechanisms orchestrating glutamine and acetate metabolism were elicited through the combination of C tracer analysis and genetic silencing, or pharmacological modulation of key metabolic enzymes including those converting glutamate into α-ketoglutarate (αKG) (and beyond) and acetate into acetyl-coenzyme A ( CoA). SUMMARY:
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Authors | Cyril Corbet, Olivier Feron |
Journal | Current opinion in clinical nutrition and metabolic care
(Curr Opin Clin Nutr Metab Care)
Vol. 18
Issue 4
Pg. 346-53
(Jul 2015)
ISSN: 1473-6519 [Electronic] England |
PMID | 26001655
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
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Chemical References |
- Acetates
- Citrates
- Ketoglutaric Acids
- Glutamine
- Acetyl Coenzyme A
- Glucose
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Topics |
- Acetates
(metabolism)
- Acetyl Coenzyme A
(metabolism)
- Cell Line, Tumor
- Citrates
(metabolism)
- Citric Acid Cycle
(drug effects)
- Glucose
(metabolism)
- Glutamine
(metabolism)
- Humans
- Hypoxia
(blood)
- Ketoglutaric Acids
(metabolism)
- Lipogenesis
(drug effects)
- Neoplasms
(metabolism)
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