Abstract | OBJECTIVE: METHODS: The data of 522 patients who underwent radical cystectomy and pelvic lymph node dissection at Department of Urology, Peking University First Hospital from 1998 to 2012, were retrospectively collected, and the lymph node mapping was performed in all the patients to determine the location of metastatic lymph nodes. RESULTS: For the 522 patients with bladder cancer, lymph node metastasis occurred in 99 patients, and the incidence of lymph node metastasis was 19.0%. The incidence at different tumor stages was: 3.7% in T1 (6/164), 10.5% in T2 (17/160), 36.7% in T3(40/107), and 41.9% in T4 (36/86). The most common involved lymph nodes were hypogastric/obturator lymph nodes (77/99, 77.8%) and external iliac lymph nodes (35/99, 35.4%). The mean number of lymph nodes dissected was 11.6 (1-51). The lymph node density (number of lymph nodes involved/number of lymph nodes removed) was 44.1%. The incidence of lymph node metastasis was statistical related to tumor stage (P < 0.01, OR 2.71,95% CI 2.13-3.44) and tumor grade (P < 0.01, OR 3.81,95% CI 1.66-8.74), while age, gender, smoke history, and weight had no statistical significance. CONCLUSION:
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Authors | Han Hao, Xin Wu, Wei Zheng, Wei Yu, Yu Fan, Qun He, Xue-song Li, Li-qun Zhou |
Journal | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
(Beijing Da Xue Xue Bao Yi Xue Ban)
Vol. 46
Issue 4
Pg. 524-7
(Aug 18 2014)
ISSN: 1671-167X [Print] China |
PMID | 25131462
(Publication Type: Journal Article)
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Topics |
- Cystectomy
- Humans
- Lymph Node Excision
- Lymph Nodes
(pathology)
- Lymphatic Metastasis
- Pelvis
- Prognosis
- Retrospective Studies
- Urinary Bladder Neoplasms
(pathology)
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