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Lymphatic Metastasis

Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system.
Also Known As:
Lymph Node Metastases; Lymphatic Metastases; Metastasis, Lymph Node; Lymph Node Metastasis
Networked: 20060 relevant articles (616 outcomes, 1693 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Neoplasm Metastasis (Metastasis)
3. Breast Neoplasms (Breast Cancer)
4. Stomach Neoplasms (Stomach Cancer)
5. Carcinoma (Carcinomatosis)

Experts

1. Zhang, Wei: 59 articles (07/2022 - 08/2002)
2. Wang, Wei: 59 articles (05/2022 - 12/2003)
3. Shariat, Shahrokh F: 56 articles (08/2022 - 03/2002)
4. Wang, Yan: 48 articles (03/2022 - 12/2004)
5. Mori, Masaki: 47 articles (08/2022 - 01/2002)
6. Li, Yan: 46 articles (01/2022 - 04/2003)
7. Wang, Jing: 44 articles (12/2022 - 01/2006)
8. Karakiewicz, Pierre I: 39 articles (08/2022 - 10/2006)
9. Zhang, Li: 39 articles (01/2022 - 07/2006)
10. Natsugoe, Shoji: 39 articles (03/2019 - 09/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Lymphatic Metastasis:
1. Cisplatin (Platino)FDA LinkGeneric
2. Proteins (Proteins, Gene)FDA Link
3. Biomarkers (Surrogate Marker)IBA
4. Vascular Endothelial Growth Factor CIBA
5. Estrogen ReceptorsIBA
6. Progesterone Receptors (Progesterone Receptor)IBA
08/01/1994 - "By multivariate analysis, c-erbB-2 failed to be an independent prognostic marker for either disease-free period or overall survival, whereas classical histopathological parameters such as presence of lymph node metastases, high number of mitoses, high histological grade (poor differentiation) and absence of progesterone receptors turned out to be of independent prognostic significance."
10/25/2023 - "(2) Univariate analysis suggested that pathological type, grade, myometrium infiltration depth, cervical interstitial infiltration, lymphatic vascular space infiltration, and progesterone receptor were all factors which significantly influence lymph node metastasis (all P<0.01); multivariate analysis suggested that the lymphatic vascular space infiltration was an independent risk factor for lymph node metastasis (OR=5.884, 95%CI: 1.633-21.211; P=0.007). "
10/05/2021 - "Ki-67 expression, progesterone receptor expression status, tumour grade and lymph node metastases were consistently associated with poor overall survival in univariate analysis but not in multivariate analysis. "
01/01/2019 - "Lymph node metastasis and progesterone receptor negativity had borderline significance in this regard (HR = 1.741 and 1.638, p = 0.099 and 0.061). "
07/01/2017 - "According to univariate analyses, progesterone receptor, HER2, T-stage, and lymph node metastasis were significant risk factors for overall survival; however, only T-stage remained significant in a multivariate analysis (p < .05). "
7. Fluorouracil (Carac)FDA LinkGeneric
8. Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
9. Docetaxel (Taxotere)FDA Link
10. CarbonIBA

Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Lymph Node Excision (Lymph Node Dissection)
4. Radiotherapy
5. Adjuvant Chemotherapy