Abstract |
A 19-year-old Asian Indian female presented with productive cough since the past one month and low grade fever since the past two weeks. She was diagnosed with pulmonary tuberculosis and treated with antitubercular drugs. Subsequently, delayed cultures of bronchoalveolar lavage fluid grew Burkholderia pseudomallei (B. pseudomallei). On follow up the patient reported significant subjective improvement and ESR progressively returned to normal. In summary, this case report raises two distinct and equally intriguing roles for B. pseudomallei, i.e. respiratory colonization and spontaneously resolving pulmonary infection. The pathogenic potential of B. pseudomallei, the etiologic agent of melioidosis, is well known. Confirmation of either colonization or spontaneous resolution, would potentially spare many patients unnecessary and expensive therapy with broad-spectrum antibiotics, and contribute to more rational usage of antibiotics, especially in co-infection with Mycobacterium tuberculosis and B. pseudomallei-two bacterial diseases with closely similar clinical, radiologic and histopathologic features.
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Authors | Kushal Naha, Barkur Ananthakrishna Shastry, Kavitha Saravu |
Journal | Asian Pacific journal of tropical medicine
(Asian Pac J Trop Med)
Vol. 7
Issue 3
Pg. 250-2
(Mar 2014)
ISSN: 2352-4146 [Electronic] India |
PMID | 24507650
(Publication Type: Case Reports, Journal Article)
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Copyright | Copyright © 2014 Hainan Medical College. Published by Elsevier B.V. All rights reserved. |
Chemical References |
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Topics |
- Adult
- Antitubercular Agents
(therapeutic use)
- Bronchoalveolar Lavage Fluid
(microbiology)
- Burkholderia pseudomallei
(isolation & purification)
- Coinfection
- Female
- Humans
- Melioidosis
(complications, diagnosis, microbiology)
- Tuberculosis, Pulmonary
(diagnosis, drug therapy, microbiology)
- Young Adult
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