Abstract | OBJECTIVE: METHODS: The study included 35 untreated hyperprolactinemic patients with pituitary adenomas, and 36 age-, gender-, and body mass index (BMI)-matched healthy controls without any known disease. Serum glucose, insulin, homeostasis model assessment of insulin resistance (HOMA-IR, lipid profile, high-sensitivity C-reactive protein ( hs-CRP), and heart-type fatty acid binding protein ( H-FABP) levels were measured. Waist and hip circumference (WC and HC) were measured in all the participants. The body fat percentage was measured, and the visceral fat and abdominal fat percentages were measured via bioelectrical impedance (BIA). In addition, carotid intima media thickness (CIMT) was measured using high-resolution B-mode ultrasound. RESULTS: The serum glucose level, HOMA-IR, triglyceride level, and SC were significantly higher in the patient group than in the control group. The hs-CRP level and CIMT were significantly higher in the hyperprolactinemic patients. Visceral and truncal fat percentages were significantly higher in the patients with prolactinoma. H-FABP levels were similar in the 2 groups, and there was a positive correlation between the prolactin (PRL) and H-FABP protein levels. CONCLUSIONS:
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Authors | Muyesser Sayki Arslan, Oya Topaloglu, Mustafa Sahin, Esra Tutal, Askin Gungunes, Evrim Cakir, Ilknur Unsal Ozturk, Basak Karbek, Bekir Ucan, Zeynep Ginis, Erman Cakal, Mustafa Ozbek, Tuncay Delibasi |
Journal | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
(Endocr Pract)
Vol. 20
Issue 5
Pg. 447-51
(May 2014)
ISSN: 1530-891X [Print] United States |
PMID | 24325995
(Publication Type: Journal Article)
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Chemical References |
- Fatty Acid-Binding Proteins
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Topics |
- Adult
- Atherosclerosis
(etiology)
- Carotid Intima-Media Thickness
- Fatty Acid-Binding Proteins
(blood)
- Female
- Humans
- Insulin Resistance
- Male
- Middle Aged
- Prolactinoma
(complications)
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