Abstract | BACKGROUND: METHODS: RESULTS: Forty-two patients developed SIADH and were treated with urea. Urea was started after a median of 7 (IQR, 5-10) days and given orally at doses of 15-30 g tid or qid for a median of 5 (IQR, 3-7) days. The median plasma sodium increase over the first day of treatment was 3 (IQR, 1-6) mEq/L. Hyponatremia was corrected in all patients, with median times to Na+ >130 and >135 mEq/L of 1 (IQR, 1-2) and 3 (IQR, 2-4) days, respectively. Urea was well tolerated, and no adverse effects were reported. CONCLUSIONS:
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Authors | Charalampos Pierrakos, Fabio Silvio Taccone, Guy Decaux, Jean-Louis Vincent, Serge Brimioulle |
Journal | Annals of intensive care
(Ann Intensive Care)
Vol. 2
Issue 1
Pg. 13
(May 30 2012)
ISSN: 2110-5820 [Electronic] Germany |
PMID | 22647340
(Publication Type: Journal Article)
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