[Experimental and clinical study of Vasosan P, a new form of pectin-enriched cholestyramine].

Abstract

The bile acid sequestering agent Vasosan P is a new form of pectin-enriched cholestyramine (20%), saccharose (5%) and sorbic acid (0.18%). In comparison with cholestyramine Vasosan P has a more marked hypolipidemic effect in experiment. Vasosan P is remarkable for good organoleptic properties. It is effective in treating patients with type IIa hyperlipoproteinemia and practically has no side effects as cholestyramine.

• Authors: V E Ryzhenkov, A M Chistiakova, V F Triufanov, L E Vasil'eva, Iu V Frolova, M A Solov'eva, O V Remezova, V T Lozovskiĭ, M Khanefel'd, V Leonkhardt
• Journal: Kardiologiia (Kardiologiia) Vol. 30 Issue 8 Pg. 77-9 (Aug 1990) ISSN: 0022-9040 [Print] Russia (Federation)
• Vernacular Title: Eksperimental'noe i klinicheskoe izuchenie vasozana P--novoĭ formy kholestiramina, obogashchennogo pektinom.
• PMID: 2255152 (Publication Type: English Abstract, Journal Article)

Chemical References

• Lipids
• Lipoproteins, VLDL
• Triglycerides
• Cholestyramine Resin
• Cholesterol

Topics

• Animals
• Cholesterol (blood)
• Cholestyramine Resin (adverse effects, therapeutic use)
• Guinea Pigs
• Humans
• Hypercholesterolemia (blood, drug therapy)
• Hyperlipoproteinemia Type II (blood, drug therapy)
• Lipid Metabolism
• Lipids (blood)
• Lipoproteins, VLDL (blood)
• Liver (metabolism)
• Rats
• Triglycerides (blood)