Abstract | CONTEXT: Clinical evaluation of gingivitis and/or periodontitis does not predict the progression or remission of the disease. Due to this diagnostic constraint, clinicians assume that the pathology has an increased risk of progression and plan treatments, despite the knowledge that all inflamed sites are not necessarily progressing. Extensive research has been carried out on gingival crevicular fluid (GCF) components that might serve as potential diagnostic markers for periodontitis. Among them alkaline phosphatase (ALP) levels in GCF has shown promise as a diagnostic marker. AIM: MATERIALS AND METHODS: This study is an in vivo longitudinal study conducted on twenty patients with localized periodontitis. The GCF was collected from the affected site prior to scaling and root planing and ALP level estimated. The probing depth and plaque index at the site were also measured for correlation. Patients were recalled after 7, 30, and 60 days for reassessment. RESULTS: The GCF ALP values showed a sustained, statistically significant decrease after treatment. There was a positive correlation with probing depth but not with plaque index measured at each interval. CONCLUSION:
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Authors | Jimly James Kunjappu, Vinod Babu Mathew, Shashikanth Hegde, Rajesh Kashyap, Rajesh Hosadurga |
Journal | Journal of oral and maxillofacial pathology : JOMFP
(J Oral Maxillofac Pathol)
Vol. 16
Issue 1
Pg. 54-7
(Jan 2012)
ISSN: 1998-393X [Electronic] India |
PMID | 22438644
(Publication Type: Journal Article)
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