Abstract | BACKGROUND: PATIENTS AND METHODS: We have reported herein three adult patients with decompensated chronic end-stage liver disease who underwent right lobe LDLT. Their general conditions had markedly deteriorated; two patients displayed massive ascites. All three subjects displayed grade IV encephalopathy with endotracheal intubation and intensive care management. Their biochemical data revealed hyperammonemia, marked cholestasis, and coagulopathy. RESULTS: After LDLT the patients recovered from coma at a mean time similar to that in coma. Preoperatively the patients exhibited acute deep coma with respiratory failure on preoperative days 5, 3, and 1 with consciousness regained on postoperative day 5, 3 and 1, respectively. CONCLUSION: We suggest that patients with acute deep coma (grade IV), who were formerly regarded as irreversible, benefit with LDLT, preventing worsening of complications, and that shows a time-dependent recovery the pretransplant comatose status.
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Authors | T-L Kao, C-C Wang |
Journal | Transplantation proceedings
(Transplant Proc)
Vol. 44
Issue 2
Pg. 421-3
(Mar 2012)
ISSN: 1873-2623 [Electronic] United States |
PMID | 22410033
(Publication Type: Case Reports, Journal Article)
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Copyright | Copyright © 2012 Elsevier Inc. All rights reserved. |
Topics |
- Acute Disease
- Chronic Disease
- Coma
(etiology, physiopathology, surgery)
- Consciousness
- End Stage Liver Disease
(complications, physiopathology, surgery)
- Female
- Hepatic Encephalopathy
(etiology, physiopathology, surgery)
- Humans
- Liver Transplantation
- Living Donors
- Male
- Middle Aged
- Recovery of Function
- Respiratory Insufficiency
(etiology)
- Severity of Illness Index
- Time Factors
- Treatment Outcome
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