Abstract | BACKGROUND:
Osteocalcin, a marker of bone formation, is also known as a regulator of glucose and fat mass. The purpose of this study was to determine the association between obesity, metabolic risks and serum osteocalcin in postmenopausal women. METHODS: RESULTS: After adjustment for age and years since menopause, WHR and VFA were negatively correlated with serum osteocalcin, but BMI did not show a significant correlation. Serum osteocalcin was negatively correlated with fasting insulin and HOMA-IR, but FPG, lipid profile, and blood pressure did not show a significant correlation. Based on multiple regression analysis, age and HOMA-IR were the most important predictors of osteocalcin. CONCLUSION:
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Authors | Suk Woo Lee, Hyun Hee Jo, Mee Ran Kim, Young Oak You, Jang Heub Kim |
Journal | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
(Gynecol Endocrinol)
Vol. 28
Issue 6
Pg. 472-7
(Jun 2012)
ISSN: 1473-0766 [Electronic] England |
PMID | 22114890
(Publication Type: Journal Article)
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Chemical References |
- Blood Glucose
- Insulin
- Osteocalcin
- C-Reactive Protein
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Topics |
- Blood Glucose
(analysis)
- Body Fat Distribution
- Body Mass Index
- C-Reactive Protein
(metabolism)
- Cross-Sectional Studies
- Female
- Humans
- Insulin
(blood)
- Insulin Resistance
(physiology)
- Metabolic Syndrome
(blood, epidemiology, etiology)
- Middle Aged
- Obesity
(blood, complications, epidemiology)
- Osteocalcin
(blood)
- Postmenopause
(blood, physiology)
- Retrospective Studies
- Risk Factors
- Waist-Hip Ratio
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