Serologic testing to verify the immune status of internationally adopted children against vaccine preventable diseases.

Abstract

Definitive immunization guidelines for internationally adopted children are lacking. We examined whether these children had serologic evidence of protection against vaccine-preventable diseases. For children with ≥3 vaccine doses, overall protection was high for diphtheria (85%), tetanus (95%), polio (93%), hepatitis B (77%), and Hib (67%). For children ≥12 months of age with ≥1 dose of measles, mumps, or rubella vaccines, 95%, 72%, and 94% were immune, respectively. Children without immunization documentation had lower immunity. Serologic testing was useful in verifying the immunization status in internationally adopted children with and without documentation of immunizations.

• Authors: Mary Allen Staat, Laura Patricia Stadler, Stephanie Donauer, Indi Trehan, Marilyn Rice, Shelia Salisbury
• Journal: Vaccine (Vaccine) Vol. 28 Issue 50 Pg. 7947-55 (Nov 23 2010) ISSN: 1873-2518 [Electronic] Netherlands
• PMID: 20937322 (Publication Type: Journal Article, Research Support, N.I.H., Extramural)
• Copyright: Copyright © 2010 Elsevier Ltd. All rights reserved.

Chemical References

• Antibodies, Viral
• Measles-Mumps-Rubella Vaccine

Topics

• Adolescent
• Adoption
• Antibodies, Viral (blood)
• Child
• Child, Preschool
• Diphtheria (prevention & control)
• Emigrants and Immigrants (statistics & numerical data)
• Haemophilus Infections (prevention & control)
• Hepatitis B (prevention & control)
• Humans
• Infant
• Measles-Mumps-Rubella Vaccine (administration & dosage)
• Poliomyelitis (prevention & control)
• Serologic Tests
• Tetanus (prevention & control)
• Vaccination (statistics & numerical data)