Mumps

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1980 relevant articles (66 outcomes, 161 trials/studies) found for this Disease

Description: An acute infectious disease caused by RUBULAVIRUS, spread by direct contact, airborne droplet nuclei, fomites contaminated by infectious saliva, and perhaps urine, and usually seen in children under the age of 15, although adults may also be affected. (From Dorland, 28th ed)

Also Known As:

Epidemic Parotitides; Epidemic Parotitis; Parotitides, Epidemic; Parotitis, Epidemic

Relationship Network

Disease Context: Research Results

Virus Diseases: 1376

RNA Virus Infections: 46

Mononegavirales Infections: 1

Paramyxoviridae Infections: 943

Rubulavirus Infections: 1

Mumps: 1980

Stomatognathic Diseases: 273

Mouth Diseases: 56

Salivary Gland Diseases: 49

Parotid Diseases: 7

Parotitis: 284

Mumps: 1980

Related Diseases

1.	Measles
2.	Rubella (German Measles)
3.	Chickenpox
4.	Infection
5.	Whooping Cough (Pertussis)

Experts

1.	Kuter, Barbara J: 6 articles (09/2006 - 06/2002)
2.	Schödel, Florian: 6 articles (09/2006 - 08/2005)
3.	Shinefield, Henry: 5 articles (09/2006 - 08/2005)
4.	Jacobson, Robert M: 4 articles (05/2008 - 01/2003)
5.	Poland, Gregory A: 4 articles (05/2008 - 01/2003)
6.	Brown, Michelle L Hoffman: 4 articles (09/2006 - 08/2005)
7.	Black, Steve: 4 articles (09/2006 - 08/2005)
8.	Xu, Jin: 4 articles (09/2006 - 08/2005)
9.	Samuel, Dhanraj: 4 articles (02/2006 - 01/2002)
10.	Pankratz, V Shane: 3 articles (05/2008 - 02/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Mumps:

1.	VaccinesIBA 01/01/1996 - "These data support other recent reports which indicate an insufficient protective efficacy of current mumps vaccines." 12/01/1986 - "These results suggest that a live attenuated mumps and MRM vaccines are safe and effective in children with various underlying diseases." 08/01/1995 - "Further studies are needed to evaluate the efficacy of the different mumps vaccines used." 07/01/2001 - "The observation of many cases of mumps and mumps-associated CNS complications in vaccinees prompted us to perform an evaluation of the efficacy of four attenuated mumps virus (Urabe, Jeryl Lynn, Rubini and S12) vaccines. " 05/01/2001 - "CONCLUSION: These data suggest that both vaccines provided equivalent protection against mumps over this 18-month period." Order ALL the reference details at left...
2.	Measles-Mumps-Rubella Vaccine (MMR Vaccine)IBA 07/01/1998 - "The new MMR vaccine 'Priorix' containing the new RIT 4385 mumps strain was safe and had a significantly improved local tolerability profile over the comparator vaccine, M-M-R II, while eliciting an at least equivalent immune response." 01/01/2007 - "The recently observed improvement in the epidemiological situation of mumps (trend towards lower and less frequent epidemic peaks) reflect the use of measles-mumps-rubella vaccine which was increasingly acquired by parents at their own expense during the last decade. " 04/25/1998 - "The poor efficacy of the mumps component of the MMR vaccine that has mainly been used in Switzerland is also evident. " 06/01/2008 - "The aim of this study was to measure the seroprevalence to mumps in Norwegian conscripts belonging to the first children vaccination cohorts that had been offered two doses of MMR vaccine. " 07/01/2006 - "Compared to no vaccine, MMR protected against mumps (odds ratio = 0.7), two doses offering best protection (odds ratio = 0.5), but the study was not large enough to detect a statistically significant difference. " Order ALL the reference details at left...
3.	AntigensIBA 05/12/1984 - "In addition, a lower mean absolute helper T cell count and an increased frequency of anergy to mumps intradermal antigen and of herpes simplex virus isolation distinguished these patients from those remaining in the cohort, who seem to be stable and in some cases to have improved." 05/01/2004 - "The aim of this study was to determine whether injection of the combination of Candida albicans, mumps, and Trichophyton skin test antigens was more efficacious than and as safe as single antigen injection. " 01/01/1986 - "Immunohistochemical studies revealed that viral antigen of HVJ was found in stria vascularis (6/11), Reissner's membrane (5/11), Organ of Corti (2/11) and viral antigen of mumps was found in stria vascularis (3/11), Reissner's membrane (1/11), Organ of Corti (1/11) in inoculated side of cochlea. " 06/01/1983 - "In this report studies were undertaken to determine whether LT induced by mumps skin test antigen (MSTA) correlated with skin test sensitivity. " 06/15/2008 - "The mean SIs in the groups were also equivalent, although IFN-gamma concentrations from cultures stimulated with mumps antigen were higher in naturally immune adults than in vaccinated adults (P < or = .01). " Order ALL the reference details at left...
4.	Mumps VaccineIBA 02/05/2009 - "CONCLUSION: The live attenuated S(79) mumps vaccine can be effective in preventing clinical mumps outbreaks." 03/15/2008 - "Mumps is vaccine-preventable, and one dose of mumps vaccine is about 80% effective against the disease. " 05/08/1987 - "Sixty-three cases of clinical mumps occurring in a New Jersey school district presented an opportunity to determine compliance with the state's 1978 mumps "new entrants" school immunization law, investigate the effect of the law on the pattern of the outbreak, estimate the efficacy of mumps vaccine, and quantitate the economic impact of the outbreak. " 11/01/2005 - "OBJECTIVE: The comparative efficacy of the three mumps vaccine strains (Jeryl-Lynn, Urabe and Rubini) was conducted in an Asian population from data arising from an epidemiological investigation of seven institutional outbreaks of mumps in Singapore. " 01/01/1999 - " Where mumps is targeted to be eliminated, countries need to add a second dose of mumps vaccine for children." Order ALL the reference details at left...
5.	Rubella VaccineIBA 09/01/2001 - "National and local pilot programmes did not succeed to promote vaccination in countees with a low measle-mumps-rubella vaccine coverage. " 03/01/1999 - "In both groups, more than 90% of infants showed an immune response to the mumps and rubella vaccine strains at 14 months of age. " 06/01/1973 - "Occurrence following combined mumps-rubella vaccine." 07/01/1997 - "Eighty-three percent of those who thought the efficacy of measles, mumps, and rubella vaccine would not be affected by a URI recommended vaccination vs only 8% of physicians who thought efficacy would decrease (P < .001). " 06/01/1988 - "These results suggest that this combined vaccine would be effective and safe in a British population and give further support for the introduction of the combined measles, mumps, and rubella vaccine to Britain." Order ALL the reference details at left...
6.	AntibodiesIBA 03/01/2009 - "A study of the age-specific seroprevalence of antibodies against mumps in children aged 3-18 years in Shahrekord aimed to establish the needof antibodies against mumps in children aged 3-18 years in Shahrekord aimed to establish the need for booster vaccinations to cover non-immune children. " 06/02/2008 - "The objective of the present study was to evaluate the seroprevalence of mumps antibodies in the Italian population, stratified by age, gender and geographical area. " 09/11/2006 - "We conducted a seroprevalence study of mumps antibodies among 353 Israeli military recruits aged 18-19, based on a representative sample of sera collected in 1999. " 04/01/1989 - "Japanese sera were shown by enzyme-linked immunosorbent assay (ELISA) to contain frequently antibodies against allantoic fluid, confirming the results obtained in our previous study on ELISA for the detection of mumps antibodies. " 05/01/1986 - "Nevertheless, m-ELISA appeared more convenient for evaluating class-specific mumps antibodies in large-scale studies, since the procedure is simpler, more rapid and less expensive than that of M-ELISA. " Order ALL the reference details at left...
7.	Immunoglobulin M (IgM)IBA 02/01/2007 - "STUDY DESIGN: The Specialist Virology Laboratory (SVC) Edinburgh distributed a serum panel to all Scottish laboratories that diagnose mumps by IgM-ELISA. " 03/08/2008 - "IgM determination was performed by indirect ELISA (Enzygnost Mumps; Dade Behring). " 10/01/2007 - "RESULTS: Thirty-one camp attendees were identified as having mumps (attack rate: 5.7%); 5 (83%) of 6 patients tested had positivity for mumps immunoglobulin M. " 02/01/2007 - "The Microimmune mumps-IgM ELISA had the best overall sensitivity in acute serum specimens. " 02/01/2007 - "CONCLUSION: The sensitivity of commercial mumps IgM-ELISAs varied greatly. " Order ALL the reference details at left...
8.	Attenuated VaccinesIBA 03/01/1997 - "The action of live attenuated vaccines against mumps is poorly understood although their clinical efficacy is beyond doubt. " 06/01/1990 - "Widespread use of safe and effective live attenuated vaccines has dramatically reduced the incidence of rubella, congenital rubella, and mumps in the United States. " 10/01/2002 - "The introduction of live attenuated vaccines, either singly or as the measles-mumps-rubella combined vaccine, has dramatically reduced the occurrence of disease and in countries where vaccine uptake is high, indigenous disease has been virtually eliminated. " 04/01/2008 - "It combines the components from two well-established, live, attenuated vaccines against measles, mumps and rubella. " 07/01/2005 - "Here, we investigated the oncolytic potential of two commercially available live attenuated vaccines, Moraten measles and Jeryl-Lynn mumps, in a murine model of intraperitoneal human ovarian cancer and compared their efficacies against a recombinant oncolytic measles virus (MV-CEA) that is being tested in a phase I clinical trial. " Order ALL the reference details at left...
9.	Tuberculin (PPD)IBA 11/01/1999 - "The differences in induration size between matched patients and controls for mumps and PPD were thus significantly greater than the corresponding differences for the C. " 03/01/1983 - "Among those with normal reactivity, positive results were found with candida-h alone in between 67-93 per cent, candida-h + mumps between 92-100 per cent and candida + mumps + PPD in 100 per cent irrespective of age." 09/01/1998 - "General immune competence was assessed by skin tests to purified protein derivative (PPD), mumps, and candida. " 10/01/1997 - "Although HIV-positive persons had markedly less tuberculin reactivity even at higher CD4+ cell counts (> 400 cells/microL), reactivity to mumps and candida was present in more than half of HIV-positive persons with low CD4+ cell counts (< or = 200 cells/microL). " 11/01/1996 - "METHODS: In keeping with prior custom, patients were seen by an experienced nurse, who performed skin testing with PPD intermediate strength as well as mumps and Candida anergy control tests in some cases, and explained the procedure. " Order ALL the reference details at left...
10.	UniversalIBA 05/01/2004 - "During the past decade mumps outbreaks have occurred in several European countries with universal vaccination programs probably due to poor efficacy of the Rubini vaccine strain. " 01/24/2008 - "Mumps incidence in the targeted MMR and universal MMR cohorts was 4.1 and 3.5 per 100,000 person-years, respectively, giving an incidence rate ratio of 1.16 (P=0.67). " 09/01/1999 - "The results suggest that, after the introduction of universal mumps vaccination in the United Kingdom in 1988, there appears to have been a switch from a predominant genotype to a heterogeneous group of strains." 09/01/1995 - "Mumps immunization in Israel was not universal at that time and most of the population had not been immunized. " 03/01/2009 - "Prevention of deafness is another important reason for assuring universal immunization against mumps." Order ALL the reference details at left...

Therapies and Procedures

1.	Immunotherapy 05/01/2005 - "CONCLUSIONS: Intralesional immunotherapy using injection of Candida, mumps, or Trichophyton skin test antigens is an effective treatment for warts, as indicated by significantly higher response rates and distant response rates in subjects receiving antigen. " 05/01/2005 - "Intralesional immunotherapy of warts with mumps, Candida, and Trichophyton skin test antigens: a single-blinded, randomized, and controlled trial." 05/01/2005 - "Intralesional immunotherapy using mumps, Candida, or Trichophyton skin test antigens has proved efficacy in the treatment of warts. " 05/01/2003 - "Immunotherapy for recalcitrant warts in children using intralesional mumps or Candida antigens." 04/01/2001 - "Intralesional injection of mumps or Candida skin test antigens: a novel immunotherapy for warts." Order ALL the reference details at left...
2.	Intralesional Injections 05/01/2003 - "To determine the efficacy of intralesional skin test antigen injection for the treatment of resistant warts in children, we treated 47 pediatric patients with one or more warts with intralesional injection of mumps or Candida skin test antigen into one wart. " 05/01/2003 - "Intralesional injection of mumps and Candida skin test antigens has been shown to be effective in the treatment of warts. " 04/01/2001 - "CONCLUSIONS: Intralesional injection of mumps or Candida antigens into warts of immune individuals represents effective treatment. " 04/01/2001 - "Intralesional injection of mumps or Candida skin test antigens: a novel immunotherapy for warts." Order ALL the reference details at left...
3.	Plasmapheresis 12/01/1996 - "A polyneuropathy developed 18 days after the onset of mumps, that improved with plasmapheresis. " Order ALL the reference details at left...
4.	Stem Cell Transplantation 11/01/2008 - "DATA SOURCES: Medline, EMBASE and Evidence Based Medicine Reviews were searched from 1966 to November 2007 for case reports or studies describing the efficacy and/or safety of live attenuated measles, mumps, rubella, or varicella vaccine in children on immunosuppression following solid organ, bone marrow or stem cell transplantation. " Order ALL the reference details at left...
5.	Chinese Traditional Medicine (Traditional Chinese Medicine) 07/01/2002 - "The root of Isatis indigotica (Cruciferae), popularly known as Ban-Lan-Gen is used in traditional Chinese medicine for seasonal febrile diseases, pestilence, mumps, eruptive diseases, inflammatory diseases with redness of skin, sore throat, etc. In this study, we evaluated the antinociceptive, antiinflammatory and antipyretic effects of Isatis indigotica root methanolic extract. " Order ALL the reference details at left...

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