Abstract |
Immune dysfunction, a well-established feature of neuroinflammatory disease, is increasingly recognized in neurodegenerative conditions. Its role is emerging as an early and active participant in neuropathology. Inflammation could be modified, with disease-slowing effects, by targeted interventions; it is also readily detectable and could serve as a source of valuable biomarkers.
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Authors | Maria Björkqvist, Edward J Wild, Sarah J Tabrizi |
Journal | Neuron
(Neuron)
Vol. 64
Issue 1
Pg. 21-4
(Oct 15 2009)
ISSN: 1097-4199 [Electronic] United States |
PMID | 19840543
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Animals
- Biomarkers
(metabolism)
- Brain
(immunology, physiopathology)
- Humans
- Immunity, Innate
- Inflammation
(immunology, physiopathology)
- Microglia
(physiology)
- Neurodegenerative Diseases
(diagnosis, immunology, physiopathology)
- Neuroimmunomodulation
(physiology)
- Spinal Cord
(immunology, physiology)
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