Abstract | OBJECTIVE: METHODS: CT scans of 49 patients with NSIP associated with CVD (15 males, 34 females; mean age, 55+/-10 years; age range, 25-76 years) were included in this retrospective study. All patients underwent a surgical biopsy. The clinical diagnosis comprised rheumatoid arthritis (RA) (n=15), systemic sclerosis (SSc) (n=8), polymyositis and dermatomyositis (PM/DM) (n=18), Sjögren's syndrome (SjS) (n=4), and mixed connective tissue disease ( MCTD) (n=4). Each CT was reviewed by two independent observers who made a clinical diagnosis based on the CT findings alone. RESULTS: The observers made a correct diagnosis for 22 (45%) of the 49 patients. A correct diagnosis was made for: RA in 7 (47%) of 15 patients; SSc in 3 (38%) of 8 patients; PM/DM in 11 (61%) of 18 patients; SjS in 1 (25%) of 4 patients. None of the 4 MCTD cases was diagnosed. CONCLUSION: It is difficult to make a correct clinical diagnosis of the various types of CVDs based solely on CT findings. However, it is probable to make a reasonably accurate clinical diagnosis in cases that show the typical CT findings, especially for PM/DM patients.
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Authors | Tadahisa Daimon, Takeshi Johkoh, Osamu Honda, Hiromitsu Sumikawa, Kazuya Ichikado, Yasuhiro Kondoh, Hiroyuki Taniguchi, Kiminori Fujimoto, Masahiro Yanagawa, Atsuo Inoue, Noriyuki Tomiyama, Hironobu Nakamura, Yukihiko Sugiyama |
Journal | Internal medicine (Tokyo, Japan)
(Intern Med)
Vol. 48
Issue 10
Pg. 753-61
( 2009)
ISSN: 1349-7235 [Electronic] Japan |
PMID | 19443969
(Publication Type: Comparative Study, Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Aged
- Arthritis, Rheumatoid
(complications, diagnostic imaging)
- Collagen Diseases
(classification, complications, diagnostic imaging)
- Dermatomyositis
(complications, diagnostic imaging)
- Diagnosis, Differential
- Female
- Humans
- Lung Diseases, Interstitial
(complications, diagnostic imaging)
- Male
- Middle Aged
- Mixed Connective Tissue Disease
(complications, diagnostic imaging)
- Retrospective Studies
- Scleroderma, Systemic
(complications, diagnostic imaging)
- Sjogren's Syndrome
(complications, diagnostic imaging)
- Tomography, X-Ray Computed
- Vascular Diseases
(classification, complications, diagnostic imaging)
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