Spinal cord involvement in Balo's concentric sclerosis.

Abstract

We present a patient with a history of myelitis, who had a steroid refractory attack of CNS inflammatory demyelinating disease that developed into cerebral concentric sclerosis of Balo after plasma exchange. The acute inflammatory disease involved the spinal cord, a phenomenon rarely demonstrated. This patient fulfilled the McDonald criteria for multiple sclerosis. Plasmapheresis did not have a beneficial effect, but the patient stabilised at high EDSS after treatment with mitoxantron.

• Authors: Karim L Kreft, S Jouke Mellema, Rogier Q Hintzen
• Journal: Journal of the neurological sciences (J Neurol Sci) Vol. 279 Issue 1-2 Pg. 114-7 (Apr 15 2009) ISSN: 1878-5883 [Electronic] Netherlands
• PMID: 19181346 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Brain (pathology)
• Diagnosis, Differential
• Diffuse Cerebral Sclerosis of Schilder (diagnosis, therapy)
• Disability Evaluation
• Female
• Humans
• Magnetic Resonance Imaging
• Middle Aged
• Multiple Sclerosis (diagnosis)
• Myelitis (complications, therapy)
• Neuropsychological Tests
• Plasma Exchange (adverse effects)
• Plasmapheresis
• Spinal Cord (pathology)
• Spinal Cord Diseases (diagnosis, therapy)