HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Demyelinating Diseases (Demyelinating Disease)

Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.
Also Known As:
Demyelinating Disease; Demyelination; Clinically Isolated CNS Demyelinating Syndrome; Clinically Isolated Syndrome, CNS Demyelinating; Demyelinating Disorders; Demyelinating Disorder; Demyelinations
Networked: 9131 relevant articles (412 outcomes, 1140 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Multiple Sclerosis
2. Inflammation (Inflammations)
3. Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
4. Neuroinflammatory Diseases
5. Gliosis

Experts

1. Lassmann, Hans: 54 articles (01/2022 - 06/2002)
2. Franklin, Robin J M: 52 articles (01/2021 - 04/2002)
3. Rodriguez, Moses: 49 articles (01/2018 - 01/2002)
4. Brück, Wolfgang: 47 articles (01/2021 - 09/2005)
5. Kipp, Markus: 40 articles (01/2022 - 05/2009)
6. Zhao, Chao: 36 articles (12/2019 - 04/2002)
7. Stangel, Martin: 35 articles (11/2021 - 11/2003)
8. Lane, Thomas E: 32 articles (11/2020 - 04/2002)
9. Baumgärtner, Wolfgang: 31 articles (01/2022 - 04/2002)
10. Beyer, Cordian: 30 articles (06/2022 - 05/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Demyelinating Diseases:
1. CuprizoneIBA
2. CytokinesIBA
3. Proteins (Proteins, Gene)FDA Link
4. Lysophosphatidylcholines (Lysophosphatidylcholine)IBA
5. Intravenous Immunoglobulins (IVIG)FDA Link
6. Adrenal Cortex Hormones (Corticosteroids)IBA
7. AntibodiesIBA
8. Peptides (Polypeptides)IBA
9. SteroidsIBA
10. NAD (NADH)IBA

Therapies and Procedures

1. Therapeutics
01/01/2019 - "In summary, we have demonstrated that SCoRe microscopy is an effective and powerful tool to perform both quantitative and qualitative analyses of compact myelin integrity in health or after injury in vivo, demonstrating its future application in high-throughput assessments and screening of the therapeutic efficacy of myelin repair therapies in preclinical animal models of demyelinating diseases."
07/01/2015 - "In light of this disparity, the efficacy of these and other therapies for acute demyelination require re-evaluation using modern, high-precision paraclinical tools capable of monitoring tissue injury.In"
07/01/2014 - "Demyelinating diseases in children can have high morbidity, and B-cell therapies hold promise for those with a severe course. "
10/01/2019 - "This more accurate model of demyelination will not only allow researchers to gain a better understanding of the CNS remyelination process in diseases such as MS, but also provides a platform technology, which could be utilized to screen and test pro-remyelination compounds which may help to find new therapeutics for progressive MS."
06/01/2003 - "Gene therapy protocols aimed to deliver therapeutic molecules into the central nervous system may represent an alternative therapeutic strategy in patients affected by inflammatory demyelinating diseases of the central nervous system where systemic therapies have shown limited therapeutic efficacy possibly owing to the blood-brain barrier, a major obstacle for the entry of therapeutic molecules into the central nervous system. "
2. Transplantation
3. Plasma Exchange
4. Intravenous Administration
5. Plasmapheresis