[Vaccination of children born from HIV-infected mothers against Haemophilus influenzae type b infection].

Abstract

Course of postvaccinal period after injection of vaccine against Haemophilus influenzae type b administered simultaneously with vaccines of Russian national immunization schedule was studied in children born from HIV-infected mothers. Good tolerability of the vaccine administered concomitantly with diphtheria-tetanus-whole cell pertussis and inactivated polio vaccines (Imovax Polio), which is comparable with tolerability in healthy children, was demonstrated. Prevaccination titers of antibodies and their dynamics during immunization process were described. Increase of levels of antibodies was detected both in the group of children with perinatal contact with HIV infection and in the group of HIV-infected children.

• Authors: M P Kostinov, D V Pakhomov, N F Snegova, T N Nikitina, T N Zinkina
• Journal: Zhurnal mikrobiologii, epidemiologii i immunobiologii (Zh Mikrobiol Epidemiol Immunobiol) 2008 Jul-Aug Issue 4 Pg. 50-5 ISSN: 0372-9311 [Print] Russia (Federation)
• PMID: 18822498 (Publication Type: Comparative Study, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Antibodies, Bacterial
• Diphtheria-Tetanus-Pertussis Vaccine
• Haemophilus Vaccines
• Poliovirus Vaccine, Inactivated

Topics

• Antibodies, Bacterial (blood)
• Diphtheria-Tetanus-Pertussis Vaccine (administration & dosage)
• Female
• Fluorescent Antibody Technique
• HIV Infections (complications, immunology)
• Haemophilus Infections (complications, immunology, prevention & control)
• Haemophilus Vaccines (adverse effects, immunology, therapeutic use)
• Haemophilus influenzae type b (immunology)
• Humans
• Immunization Schedule
• Immunization, Secondary
• Infant
• Male
• Poliovirus Vaccine, Inactivated (administration & dosage)
• Pregnancy
• Pregnancy Complications, Infectious (virology)
• Time Factors
• Vaccination