Abstract | OBJECTIVE: RESEARCH DESIGN AND METHODS: In the Study on Lifestyle intervention and Impaired glucose tolerance Maastricht, 147 men and women with impaired glucose tolerance (IGT) were randomized to either a combined diet-and-exercise intervention or a control program. At baseline and after 1 year, an oral glucose tolerance test, an exercise test, and anthropometric measurements were performed. After 1 year, complete data of 103 subjects (50 intervention and 53 control subjects) were obtained. RESULTS: CONCLUSIONS: Changes in leptin concentration were related to improvements in insulin sensitivity independent of changes in body composition.
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Authors | Eva Corpeleijn, Edith J M Feskens, Eugène H J M Jansen, Marco Mensink, Wim H M Saris, Ellen E Blaak |
Journal | Diabetes care
(Diabetes Care)
Vol. 30
Issue 12
Pg. 3125-7
(Dec 2007)
ISSN: 1935-5548 [Electronic] United States |
PMID | 17890316
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Adipokines
- Adiponectin
- Biomarkers
- Leptin
- Resistin
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Topics |
- Adipokines
(blood)
- Adiponectin
(blood)
- Biomarkers
(blood)
- Body Size
- Diabetes Mellitus, Type 2
(blood, epidemiology, prevention & control)
- Diet, Diabetic
- Exercise
- Female
- Glucose Intolerance
(blood, complications)
- Humans
- Leptin
(blood)
- Life Style
- Male
- Reference Values
- Resistin
(blood)
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