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Proliferating Cell Nuclear Antigen (PCNA)

Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.
Also Known As:
PCNA; Antigen, Proliferating Cell Nuclear
Networked: 6520 relevant articles (165 outcomes, 815 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Zhang, Wei: 23 articles (04/2022 - 01/2002)
2. Rao, Chinthalapally V: 15 articles (01/2021 - 06/2006)
3. Zhang, Jing: 13 articles (10/2022 - 03/2002)
4. Liu, Yang: 13 articles (01/2021 - 01/2004)
5. Malkas, Linda H: 13 articles (06/2020 - 09/2006)
6. Tanaka, Takuji: 13 articles (09/2018 - 02/2002)
7. Wang, Yan: 12 articles (08/2022 - 05/2007)
8. Mohammed, Altaf: 12 articles (01/2021 - 12/2011)
9. Wang, Wei: 12 articles (03/2017 - 01/2005)
10. Agarwal, Rajesh: 12 articles (01/2016 - 03/2002)

Related Diseases

1. Neoplasms (Cancer)
2. Inflammation (Inflammations)
3. Carcinogenesis
4. Carcinoma (Carcinomatosis)
5. Neoplasm Metastasis (Metastasis)

Related Drugs and Biologics

1. Proliferating Cell Nuclear Antigen (PCNA)
2. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
3. Proteins (Proteins, Gene)
4. Caspase 3 (Caspase-3)
5. Biomarkers (Surrogate Marker)
6. Collagen
7. Antioxidants
8. Enzymes
9. Cytokines
10. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Radiotherapy
4. Transplantation
5. Lasers (Laser)