Abstract | BACKGROUND: OBJECTIVE: METHODS: Patients with inflammatory myositis of recent onset who had not received treatment were evaluated for associated myocarditis by magnetic resonance imaging (MRI) and reinvestigated after treatment with high dose corticosteroids and immunosuppressors. RESULTS: CONCLUSION: Treatment with intravenous methylprednisolone followed by prednisone and immunosuppressive therapy seems to be effective for treating myocardial involvement in patients with idiopathic inflammatory myopathies, either alone or presenting as overlap syndromes. Cardiovascular MRI is a non-invasive technique that may be a powerful tool for diagnosis and monitoring of myocardial inflammation in this setting.
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Authors | Y Allanore, O Vignaux, L Arnaud, X Puéchal, S Pavy, D Duboc, P Legmann, A Kahan |
Journal | Annals of the rheumatic diseases
(Ann Rheum Dis)
Vol. 65
Issue 2
Pg. 249-52
(Feb 2006)
ISSN: 0003-4967 [Print] England |
PMID | 16410529
(Publication Type: Case Reports, Journal Article, Review)
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Chemical References |
- Adrenal Cortex Hormones
- Antibodies, Antinuclear
- Autoantibodies
- Immunosuppressive Agents
- Jo-1 antibody
- Prednisolone
- Methylprednisolone
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Topics |
- Adrenal Cortex Hormones
(therapeutic use)
- Adult
- Antibodies, Antinuclear
(analysis, immunology)
- Autoantibodies
(analysis)
- Female
- Humans
- Immunosuppressive Agents
(therapeutic use)
- Magnetic Resonance Imaging
- Male
- Methylprednisolone
(therapeutic use)
- Middle Aged
- Myocarditis
(diagnosis, drug therapy, immunology)
- Myocardium
(immunology, pathology)
- Myositis
(drug therapy, immunology, pathology)
- Prednisolone
(therapeutic use)
- Treatment Outcome
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