Transcranial Direct Current Stimulation

A technique of brain electric stimulation therapy which uses constant, low current delivered via ELECTRODES placed on various locations on the scalp.

Also Known As:

Anodal Stimulation Transcranial Direct Current Stimulation; Anodal Stimulation tDCS; Cathodal Stimulation Transcranial Direct Current Stimulation; Cathodal Stimulation tDCS; Repetitive Transcranial Electrical Stimulation; Transcranial Alternating Current Stimulation; Transcranial Electrical Stimulation; Transcranial Random Noise Stimulation; tDCS; Anodal Stimulation tDCSs; Cathodal Stimulation tDCSs; Electrical Stimulation, Transcranial; Electrical Stimulations, Transcranial; Stimulation tDCS, Anodal; Stimulation tDCS, Cathodal; Stimulation tDCSs, Anodal; Stimulation tDCSs, Cathodal; Stimulation, Transcranial Electrical; Stimulations, Transcranial Electrical; Transcranial Electrical Stimulations; tDCS, Anodal Stimulation; tDCS, Cathodal Stimulation; tDCSs, Anodal Stimulation; tDCSs, Cathodal Stimulation

Networked: 3687 relevant articles (747 outcomes, 1427 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Fregni, Felipe: 180 articles (03/2022 - 09/2005)
2.	Bikson, Marom: 81 articles (07/2022 - 10/2010)
3.	Nitsche, Michael A: 78 articles (04/2022 - 09/2005)
4.	Padberg, Frank: 53 articles (04/2022 - 01/2009)
5.	Pascual-Leone, Alvaro: 47 articles (01/2022 - 09/2005)
6.	Venkatasubramanian, Ganesan: 44 articles (11/2021 - 07/2013)
7.	Palm, Ulrich: 43 articles (11/2022 - 01/2009)
8.	Caumo, Wolnei: 40 articles (02/2022 - 01/2012)
9.	Priori, Alberto: 37 articles (12/2022 - 11/2008)
10.	Brunoni, Andre R: 37 articles (11/2022 - 08/2011)

Related Diseases

1.	Stroke (Strokes) 10/24/2023 - "To evaluate the available evidence to determine which tDCS polarity has the best results in improving UE motor function after stroke. " 10/24/2023 - "The cathodic (c-tDCS), anodic (a-tDCS), and bihemispheric stimulation have demonstrated efficacy in the management of the paretic upper extremity (UE) after stroke, but it has not been determined which stimulation polarity has, so far, shown the best results. " 10/01/2023 - "After taVNS, excitatory stimulation protocols (intermittent TBS, anodal tDCS, and HF-rTMS) are most effective in improving motor function and ADLs after acute/sub-acute (SMD range 0.53-1.63) and chronic stroke (SMD range 0.39-1.16). " 01/01/2021 - "Objective: Combining transcranial direct current stimulation (tDCS) and repetitive gait training may be effective for gait performance recovery after stroke; however, the timing of stimulation to obtain the best outcomes remains unclear. " 01/01/2019 - "The primary objective of the present work was to test the efficacy of multiple sessions of tDCS combined with a highly standardized and progressive resistance training program of the affected upper limb in individuals in the chronic phase of recovery after a stroke. "
2.	Pain (Aches) 07/14/2013 - "Given that most published studies on 4x1 HD-tDCS have targeted the primary motor cortex (M1), particularly for pain-related outcomes, the purpose of this article is to systematically describe its use for M1 stimulation, as well as the considerations to be taken for safe and effective stimulation. " 01/01/2021 - "PERSPECTIVE: Medial prefrontal HD-tDCS did not alter pain, psychological nor psychophysical outcomes, though correlational analysis suggested response may depend on baseline pain inhibitory efficacy, with best potential effects in patients with severe impairments in descending pain inhibitory mechanisms. " 01/01/2019 - "Two studies reported significant pain improvement with tDCS applied over M1 while the other two failed to demonstrate significant effects compared to placebo. " 12/01/2023 - "However, the pain-related behaviors of rats were significantly improved after tDCS treatment. " 12/01/2023 - "Notably, anodal tDCS applied over the primary motor cortex (M1) appears to be particularly effective in alleviating pain in patients with knee OA. "
3.	Schizophrenia (Dementia Praecox) 01/01/2019 - "The promising results regarding the fast-acting beneficial effects of tDCS on cognitive insight and planning ability in schizophrenia require confirmation in future replication studies." 01/01/2018 - "To quantify the efficacy of double-blind randomized controlled trials (RCT) of tDCS and rTMS for the positive and negative symptoms of schizophrenia and identify significant moderators relating to patient-related features and stimulation parameters. " 10/01/2016 - "Therefore, gamma (γ) tACS may be even more effective than tDCS in improving working memory in schizophrenia. " 01/01/2022 - "Promising results are reported for the treatment of negative symptoms with tDCS, tACS and tRNS and could thus represent new therapeutic options in the treatment of schizophrenia. " 01/01/2018 - "Transcranial direct current stimulation (tDCS) has been shown to be effective in treating some of the symptoms of schizophrenia. "
4.	Aphasia (Dysphasia) 07/01/2015 - "Most of transcranial direct current stimulation (tDCS) studies in aphasia have already shown that significant changes in language performance could be improved by increased monitoring of the perilesional cortex in the left lesioned hemisphere with excitatory anodal tDCS (A-tDCS). " 01/01/2022 - "Moreover, tDCS is also effective in PSD patients with aphasia or CPSP. " 01/01/2020 - " treatment with tDCS and speech and language therapy (SLT) was effective in a patient with subacute thalamic aphasia, who showed improvement in all aspects of linguistic and behavioural communication." 01/01/2019 - "Sub-analyses indicated that while rTMS can be considered effective for both subacute and chronic patients, tDCS seems adequate only for chronic aphasia. " 01/01/2022 - "During the last decade, studies using anodal transcranial Direct Current Stimulation (atDCS) have yielded promising results in patients with aphasia. "
5.	Fatigue 01/01/2021 - "The study results revealed that the tDCS trial significantly increase the countermovement jump performance (p = 0.04), decrease the sprinting time (p = 0.016), and had improved fatigue index during the sprinting process (p = 0.009). " 05/11/2023 - "Furthermore, tDCS did not exert a significant improvement in walking ability, but it appeared to influence fatigue. " 01/01/2022 - "tDCS significantly improved the participants' emotional status, including depression, fatigue, and energy level. " 01/01/2022 - "Furthermore, tDCS had favorable effects on fatigue in MS patients with low physical disability but not those with high physical disability, and additionally improved cognitive function. " 01/01/2021 - "The active group presented significantly greater reductions in fatigue as measured by the EULAR Sjögren's Syndrome Patient Reported Index after five tDCS sessions [mean group difference: 1.40; 95%CI -2.33, -0.48; effect size 1.04]. "

Related Drugs and Biologics

1.	salicylhydroxamic acid (SHAM)
2.	Analgesics (Analgesic Drugs)
3.	TES
4.	Therapeutic Uses
5.	Antidepressive Agents (Antidepressants)
6.	Antipsychotic Agents (Antipsychotics)
7.	Placebos
8.	Opioid Analgesics (Opioids)
9.	2- benzylidene- 3- (cyclohexylamino)- 2,3- dihydro- 1H- inden- 1- one
10.	Brain-Derived Neurotrophic Factor (BDNF)

Related Therapies and Procedures

1.	Transcranial Direct Current Stimulation
2.	Transcranial Magnetic Stimulation
3.	Therapeutics
4.	Electrodes (Electrode)
5.	Cognitive Training