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Hypertriglyceridemic Waist

A screening phenotype consisting of both elevated WAIST CIRCUMFERENCE and elevated fasting TRIGLYCERIDES level.
Also Known As:
Enlarged Waist Elevated Triglycerides; Waist, Hypertriglyceridemic
Networked: 112 relevant articles (2 outcomes, 27 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Type 2 Diabetes Mellitus (MODY)
2. Metabolic Syndrome (Dysmetabolic Syndrome X)
3. Abdominal Obesity
4. Overweight
5. Coronary Artery Disease (Coronary Atherosclerosis)

Experts

1. Després, Jean-Pierre: 12 articles (01/2018 - 07/2002)
2. Lemieux, Isabelle: 10 articles (01/2018 - 07/2002)
3. Bergeron, Jean: 6 articles (08/2012 - 07/2002)
4. Gaudet, Daniel: 6 articles (08/2012 - 07/2002)
5. Lamarche, Benoît: 5 articles (08/2012 - 12/2003)
6. Perron, Patrice: 5 articles (08/2012 - 07/2002)
7. Alméras, Natalie: 4 articles (01/2018 - 07/2002)
8. Blackburn, Patricia: 4 articles (08/2012 - 12/2003)
9. Marcadenti, Aline: 3 articles (01/2021 - 09/2015)
10. Yin, Fu-Zai: 3 articles (01/2019 - 09/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hypertriglyceridemic Waist:
1. Insulin (Novolin)FDA Link
2. Apolipoproteins B (ApoB)IBA
3. ApolipoproteinsIBA
12/01/2003 - "Subjects characterized by "hypertriglyceridemic waist" (waist > or = 90 cm and fasting TG > or = 2.0 mmol/l) showed the highest TRL-TG concentrations (P < 0.0001) throughout the entire postprandial period (8 h) as well as elevated concentrations of apolipoprotein (apo) B-48 and apo B-100 in all TRL fractions (large, medium and small) compared to subjects with low fasting TG levels who had waist girth values either above or below 90 cm. These higher postprandial TRL-TG levels among carriers of the "hypertriglyceridemic waist" phenotype also led to significantly greater postprandial TG-total area under the curve (AUC) in total TRLs resulting mainly from the increased concentrations of large- and medium-sized TRLs. "
10/01/2013 - "The metabolic triad [fasting insulin, apolipoprotein B, and low-density lipoporotein (LDL) peak particle density] is characteristic of increased intra-abdominal adipose tissue and insulin resistance and can be predicted by the simple and adoptable screening tool, the hypertriglyceridemic waist. "
09/21/2010 - "Compared with participants who had a waist circumference and triglyceride level below the threshold, those with the hypertriglyceridemic-waist phenotype had higher blood pressure indices, higher levels of apolipoprotein B and C-reactive protein, lower levels of high-density lipoprotein cholesterol and apolipoprotein A-I, and smaller low-density lipoprotein particles. "
08/01/2009 - "Men with the hypertriglyceridemic waist phenotype were characterized by alterations in their lipoprotein-lipid profile that included small low-density lipoprotein particles, increased apolipoprotein B and insulin levels, as well as reduced adiponectin concentrations, which were similar to individuals meeting the NCEP-ATP III or the IDF criteria. "
4. Apolipoprotein B-100 (Apo B 100)IBA
5. Apolipoprotein B-48IBA
6. Triglycerides (Triacylglycerol)IBA
02/10/2016 - "The hypertriglyceridemic waist (HW) phenotype has been shown to be strongly associated with metabolic abnormalities; however, to date, no study has reported the prediction of metabolic abnormalities using the HW phenotype along with waist circumference (WC) and the triglyceride (TG) level or various phenotypes consisting of an individual anthropometric index combined with the TG level. "
12/01/2023 - "Patients were classified into four phenotype groups according to their waist circumference and triglyceride levels: normal waist circumference and normal triglycerides; normal waist circumference and elevated triglycerides; enlarged waist circumference and normal triglycerides; and enlarged waist circumference and triglycerides, namely hypertriglyceridemic waist (HTGW) phenotype. "
10/24/2022 - " Background: The hypertriglyceridemic waist (HTGW) phenotype is characterized by concomitant increases in waist circumference (WC) and blood triglyceride levels (TG), which has been identified as a predictor of metabolic disorders. "
09/01/2022 - "In this cross-sectional study, a total of 9015 participants (age 40-79 years) were recruited and grouped into four phenotypes, as follows: NWNT: normal waist-normal triglyceride; NWET: normal waist-elevated triglycerides; EWNT: elevated waist-normal triglycerides; and hypertriglyceridemic waist (HTGW). "
01/01/2022 - "The hypertriglyceridemic-waist (HTGW) phenotype was defined as the presence of an elevated waist circumference (WC) and elevated triglyceride (TG) concentration. "
7. Glucose (Dextrose)FDA LinkGeneric
8. LipidsIBA
9. HDL CholesterolIBA
10. Vitamin DFDA LinkGeneric

Therapies and Procedures

1. Bariatric Surgery
2. Renal Dialysis (Hemodialysis)
3. Surgical Amputation (Amputations)
4. Glycemic Control