Minichromosome Maintenance Complex Component 8

A minichromosome maintenance protein that forms a hexameric complex with MINICHROMSOME MAINTENANCE COMPLEX COMPONENT 9. The MCM8-MCM9 helicase complex is involved in HOMOLOGOUS RECOMBINATION REPAIR following the formation of DNA interstrand cross-links.

Also Known As:

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Du, Juan: 1 article (01/2020)
2.	Guo, Sheng: 1 article (01/2020)
3.	He, Wen-Bin: 1 article (01/2020)
4.	Li, Pin: 1 article (01/2020)
5.	Lin, Ge: 1 article (01/2020)
6.	Lu, Guang-Xiu: 1 article (01/2020)
7.	Meng, Lan-Lan: 1 article (01/2020)
8.	Tan, Chen: 1 article (01/2020)
9.	Tan, Yue-Qiu: 1 article (01/2020)
10.	Wang, Fei: 1 article (01/2020)

Related Diseases

1.	Primary Ovarian Insufficiency 01/01/2019 - "Minichromosome maintenance complex component 8 and 9 gene expression in the menstrual cycle and unexplained primary ovarian insufficiency." 11/01/2016 - "To investigate whether mutations in the minichromosome maintenance complex component 8 (MCM8) gene were present in 192 patients with sporadic primary ovarian insufficiency (POI). " 11/01/2016 - "Minichromosome maintenance complex component 8 mutations cause primary ovarian insufficiency." 01/01/2020 - "Minichromosome maintenance complex component 8 (MCM8) is responsible for homologous recombination and DNA double-strand breaks (DSBs) repair and is the cause of primary ovarian insufficiency (POI), which is seldom diagnosed in adolescents and children. "
2.	Female Infertility 01/01/2020 - "Premature ovarian insufficiency (POI) is one major cause of female infertility, minichromosome maintenance complex component 8 (MCM8) has been reported to be responsible for POI. "

Related Drugs and Biologics

1.	DNA (Deoxyribonucleic Acid)