Pudendal Neuralgia

Pain associated with a damaged PUDENDAL NERVE. Clinical features may include positional pain with sitting in the perineal and genital areas, sexual dysfunction and FECAL INCONTINENCE and URINARY INCONTINENCE.

Also Known As:

Pudendal Canal Entrapment Syndrome; Pudendal Nerve Entrapment; Pudendal Nerve Entrapment Syndrome; Pudendal Neuropathy; Entrapment, Pudendal Nerve; Entrapments, Pudendal Nerve; Nerve Entrapment, Pudendal; Nerve Entrapments, Pudendal; Neuralgias, Pudendal; Neuropathies, Pudendal; Neuropathy, Pudendal; Pudendal Nerve Entrapments; Pudendal Neuralgias; Pudendal Neuropathies; Neuralgia, Pudendal

Networked: 82 relevant articles (18 outcomes, 7 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Pain (Aches)
2.	Fecal Incontinence
3.	Pudendal Neuralgia
4.	Pelvic Pain
5.	Lower Urinary Tract Symptoms

Experts

1.	Labat, Jean-Jacques: 3 articles (01/2017 - 03/2005)
2.	Robert, Roger: 3 articles (01/2017 - 03/2005)
3.	Absil, Fabienne: 2 articles (04/2021 - 01/2021)
4.	Aoun, Fouad: 2 articles (04/2021 - 01/2021)
5.	Bollens, Renaud: 2 articles (04/2021 - 01/2021)
6.	Calabrò, Rocco Salvatore: 2 articles (04/2021 - 05/2010)
7.	Mjaess, Georges: 2 articles (04/2021 - 01/2021)
8.	Castellanos, Mario E: 2 articles (12/2019 - 05/2012)
9.	Chhabra, Avneesh: 2 articles (01/2019 - 01/2017)
10.	Labat, J J: 2 articles (01/2017 - 01/2017)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pudendal Neuralgia:

1.	Analgesics (Analgesic Drugs)IBA 10/01/1993 - "The author concludes that the presence of pudendal neuralgia should prompt a search for an underlying cause, and that this severe neuropathic pain syndrome is effectively managed with adjuvant analgesics." 08/01/2021 - "Adding TENS to physical therapy exercise program is more effective than physical therapy program alone in improving pain in male patients with pudendal neuralgia as measured by numerical pain rating scale and daily analgesic intake dose."
2.	SiliconesIBA 12/01/2004 - "Injection of silicone biomaterial provided a marked improvement in fecal continence and quality of life in patients with internal sphincter dysfunction, despite the presence of pudendal neuropathy."
3.	Biocompatible Materials (Biomaterials)IBA 12/01/2004 - "Injection of silicone biomaterial provided a marked improvement in fecal continence and quality of life in patients with internal sphincter dysfunction, despite the presence of pudendal neuropathy."
4.	Adrenal Cortex Hormones (Corticosteroids)IBA 01/01/2017 - "Authors' reply re: Adding corticosteroids to the pudendal nerve block for pudendal neuralgia: a randomised, double-blind, controlled trial." 01/01/2017 - "Re: Adding corticosteroids to the pudendal nerve block for pudendal neuralgia: a randomised, double-blind, controlled trial." 01/01/2017 - "Adding corticosteroids to the pudendal nerve block for pudendal neuralgia: a randomised, double-blind, controlled trial." 01/01/2017 - "To compare the effect of corticosteroids combined with local anaesthetic versus local anaesthetic alone during infiltrations of the pudendal nerve for pudendal nerve entrapment. "
5.	SteroidsIBA 01/01/2017 - "Steroid infiltrations do not improve the results of local anaesthetic infiltrations in pudendal neuralgia." 05/01/2009 - "Retrospective review of 49 patients with suspected pudendal neuralgia who underwent one or multiple injections of local anesthetics and steroids. "
6.	Local AnestheticsIBA 02/01/2000 - "Severe pelvic pain secondary to pudendal neuropathy can be treated with repeated local anesthetic nerve blocks or with surgical decompression of the nerve. " 05/01/2009 - "Retrospective review of 49 patients with suspected pudendal neuralgia who underwent one or multiple injections of local anesthetics and steroids. "
7.	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 01/01/2018 - "The combination of tests provided a diagnosis of pudendal neuropathy in all patients, resulting in an accurate and timely explanation of the neurogenic basis of their CPP symptoms. " 01/01/2019 - "The term "CPP" encompasses a number of treatment-resistant conditions like pudendal neuralgia, interstitial cystitis, coccygodynia, vulvodynia. "
8.	Mitomycin (Mitomycin-C)FDA LinkGeneric 01/01/2020 - "Post-Transurethral Resection of Bladder Tumor Bladder Perforation Resulting in Mitomycin C Extravasation, Pudendal Neuralgia, and Ureterohydronephrosis."
9.	Oxygen (Dioxygen)IBA 11/01/2003 - "Hyperbaric oxygen in the treatment of fecal incontinence secondary to pudendal neuropathy."
10.	Oxycodone (Oxycontin)FDA LinkGeneric 05/01/2021 - "To explore the clinical efficacy, safety, and prevention of major adverse reactions of the non-steroidal anti-inflammatory drug celecoxib combined with OxyContin and Pregabalin in the treatment of cancerous pudendal neuralgia. " 05/01/2021 - "When treating patients with cancerous pudendal neuralgia with OxyContin and Pregabalin, the addition of celecoxib has a significant effect, which can effectively improve the patient's pain, improve their quality of life to a certain extent, and reduce the consumption of OxyContin. "

Therapies and Procedures

1.	Decompression 01/01/2021 - "This perspective assessed the efficacy of laparoscopic pudendal nerve and artery decompression in young patients suffering from refractory ED, associated to a pudendal nerve entrapment syndrome. " 01/01/2017 - "The purpose of this study was to describe the course of the nerve and its variants in a population of patients with pudendal neuralgia in order to guide the surgeon in the choice of surgical approach for pudendal nerve decompression. " 01/01/2023 - "Pudendal Neuralgia: Two case reports with laparoscopic nerve decompression." 04/01/2021 - "When clinical features of pudendal nerve entrapment are present, laparoscopic transperitoneal pudendal decompression relieves LUTS in these young males." 01/01/2016 - "Pudendal neuralgia after pelvic surgery using mesh: Case reports and laparoscopic pudendal nerve decompression."
2.	Nerve Block (Nerve Blocks) 04/18/2022 - "Objectives: To investigate the efficacy and safety of an improved ultrasound-guided pulsed radiofrequency (PRF) and nerve block (NB) for patients with pudendal neuralgia (PN). " 01/01/2019 - "Role of nerve block as a diagnostic tool in pudendal nerve entrapment." 07/01/2014 - "CT-guided nerve block for pudendal neuralgia: diagnostic and therapeutic implications." 07/01/2004 - "Many physicians and patients are hesitant to pursue diagnostic nerve blocks to confirm the diagnosis of pudendal neuralgia secondary to significant patient discomfort, the need for special equipment, and the risk in the traditionally described approach. " 06/01/2003 - "Pudendal nerve entrapment was diagnosed clinically, with computed tomography-guided nerve blocks providing temporary relief. "
3.	Therapeutics 02/01/2023 - "Dorsal Root Ganglion Stimulation Therapy for Refractory Idiopathic Pudendal Neuralgia." 08/01/2015 - "Fifteen women with pudendal neuralgia not responsive to 3-months medical therapy were examined clinically, with VAS score, validated SF-36 questionnaire, and pudendal nerve motor terminal latency (PNMTL). " 06/01/2013 - "Magnetic resonance imaging-guided perineural therapy as a treatment option in young adults with pudendal nerve entrapment syndrome." 05/01/2005 - "To describe the clinical and electrodiagnostic findings, therapies, and outcomes of patients with pudendal neuralgia. " 02/01/2000 - "We believe this technique warrants further evaluation and application in instances where noninvasive therapy of pudendal neuropathy is indicated."
4.	Psychology Biofeedback (Biofeedback) 12/01/2009 - "The poorest results occurred in women with pudendal neuropathy, or patients who had previously received biofeedback treatment. " 06/01/1999 - "Patients with severe incontinence (incontinence to solids) and pudendal neuropathy failed to improve the amplitude and duration of their maximum voluntary contraction after biofeedback therapy. " 11/01/2003 - "Idiopathic fecal incontinence secondary to pudendal neuropathy is usually treated with biofeedback, which shows improvement in only 50 percent of patients. " 06/01/1999 - "It has been suggested that the severity of fecal incontinence, the presence of pudendal neuropathy, or an external anal sphincter defect does not preclude clinical improvement with biofeedback therapy. " 06/01/1999 - "In patients with fecal incontinence, the severity of symptoms and pudendal neuropathy should be considered as two factors of poor prognosis of favorable manometric results after biofeedback therapy. "
5.	Sutures (Suture) 08/01/2008 - "Removal of sutures, even long after surgery, can result in clinically significant improvement in pain symptoms and sexual function in patients with pudendal nerve entrapment." 10/01/2022 - "To analyse the efficacy of sacrospinous ligament (SSL) suture removal on the reduction of pain symptoms in the case of suspected pudendal nerve entrapment after sacrospinous ligament fixation (SSLF). "