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gamma-Butyrobetaine Dioxygenase

An enzyme that catalyzes the HYDROXYLATION of gamma-butyrobetaine to L-CARNITINE. It is the last enzyme in the biosynthetic pathway of L-CARNITINE and is dependent on alpha-ketoglutarate; IRON; ASCORBIC ACID; and OXYGEN.
Also Known As:
4-Trimethylaminobutyrate, 2-Oxoglutarate Oxygen Oxidoreductase (3-Hydroxylating); Butyrobetaine Hydroxylase; Trimethylaminobutyrate Hydroxylase; gamma-Butyrobetaine Hydroxylase; gamma-Butyrobetaine, 2-Oxoglutarate Dioxygenase; gamma-Butyrobetaine,2-Oxoglutarate Dioxygenase; 2-Oxoglutarate Dioxygenase gamma-Butyrobetaine; Dioxygenase gamma-Butyrobetaine, 2-Oxoglutarate; Dioxygenase, gamma-Butyrobetaine; Dioxygenase, gamma-Butyrobetaine,2-Oxoglutarate; Hydroxylase, Butyrobetaine; Hydroxylase, Trimethylaminobutyrate; Hydroxylase, gamma-Butyrobetaine; gamma Butyrobetaine Dioxygenase; gamma Butyrobetaine Hydroxylase; gamma Butyrobetaine, 2 Oxoglutarate Dioxygenase; gamma Butyrobetaine,2 Oxoglutarate Dioxygenase
Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Matsuura, N: 3 articles (11/2000 - 05/2000)
2. Miyake, H: 3 articles (11/2000 - 05/2000)
3. Hayashi, Y: 3 articles (11/2000 - 05/2000)
4. Tajima, K: 3 articles (11/2000 - 05/2000)
5. Kirimoto, T: 3 articles (11/2000 - 05/2000)
6. Nakano, M: 2 articles (06/2000 - 05/2000)
7. Makarova, Elina: 1 article (07/2014)
8. Cirule, Helena: 1 article (07/2014)
9. Lola, Daina: 1 article (07/2014)
10. Pugovics, Osvalds: 1 article (07/2014)

Related Diseases

1. Myocardial Infarction
2. Heart Failure
3. Ischemia
4. Hypothyroidism
5. Hyperthyroidism

Related Drugs and Biologics

1. Carnitine (L-Carnitine)
2. 3-(2,2,2-trimethylhydrazine)propionate