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Sphingolipids

A class of membrane lipids that have a polar head and two nonpolar tails. They are composed of one molecule of the long-chain amino alcohol sphingosine (4-sphingenine) or one of its derivatives, one molecule of a long-chain acid, a polar head alcohol and sometimes phosphoric acid in diester linkage at the polar head group. (Lehninger et al, Principles of Biochemistry, 2nd ed)
Also Known As:
Lysosphingolipids; Sphingolipid
Networked: 3208 relevant articles (55 outcomes, 380 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Hannun, Yusuf A: 47 articles (01/2021 - 08/2004)
2. Spiegel, Sarah: 42 articles (12/2021 - 04/2002)
3. Kester, Mark: 32 articles (01/2022 - 12/2002)
4. Obeid, Lina M: 31 articles (01/2021 - 02/2008)
5. Gulbins, Erich: 29 articles (01/2022 - 12/2006)
6. Bielawski, Jacek: 29 articles (01/2021 - 09/2006)
7. Chabowski, Adrian: 28 articles (09/2022 - 11/2012)
8. Levade, Thierry: 28 articles (11/2020 - 12/2002)
9. Ogretmen, Besim: 27 articles (04/2022 - 08/2004)
10. Hornemann, Thorsten: 20 articles (01/2022 - 09/2009)

Related Diseases

1. Neoplasms (Cancer)
2. Atherosclerosis
3. Inflammation (Inflammations)
4. Insulin Resistance
5. Hyperlipidemias (Hyperlipidemia)

Related Drugs and Biologics

1. Sphingolipids
2. Ceramides
3. Enzymes
4. Sphingosine
5. Lipids
6. Glycerophospholipids (Phosphoglycerides)
7. Fingolimod Hydrochloride (FTY720)
8. sphingosine 1-phosphate (sphingosine-1-phosphate)
9. Phospholipids (Phosphatides)
10. Acids

Related Therapies and Procedures

1. Therapeutics
2. Immunotherapy
3. Chemoprevention
4. Moxibustion
5. Radiotherapy