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Trisaccharides

Oligosaccharides containing three monosaccharide units linked by glycosidic bonds.

Also Known As:

Trisaccharide

Networked: 123 relevant articles (3 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Polysaccharides: 15383
  - Oligosaccharides: 3566
    - Trisaccharides: 123

Experts

1.	Quinn, Conrad P: 3 articles (01/2018 - 05/2011)
2.	Bovin, N V: 3 articles (10/2014 - 03/2001)
3.	Belenki, Alexey: 2 articles (03/2018 - 01/2018)
4.	Donovan, Marissa: 2 articles (03/2018 - 01/2018)
5.	Klodnitsky, Helen: 2 articles (03/2018 - 01/2018)
6.	Leonard, John: 2 articles (03/2018 - 01/2018)
7.	Lillie, James: 2 articles (03/2018 - 01/2018)
8.	Lund, Troy C: 2 articles (03/2018 - 01/2018)
9.	Makino, Elina: 2 articles (03/2018 - 01/2018)
10.	Marshall, John: 2 articles (03/2018 - 01/2018)

Related Diseases

1.	Lepromatous Leprosy 06/01/1987 - "It had already been demonstrated that only those trisaccharides containing an intact, terminal 3,6-di-O-methyl-beta-D-glucopyranosyl unit are effective in inhibiting the specific binding between PGL-I and anti-PGL-I immunoglobulin M antibodies in human lepromatous leprosy sera." 12/01/2011 - "PGL-I, despite its extreme lipophilicity due to its inherent phthiocerol dimycocerosyl component, is highly antigenic evoking high titre IgM antibodies in lepromatous leprosy patients, attributable largely to the unique 3,6-di-O-methyl-beta-D-glucosyl entity at the non-reducing terminus of its trisaccharide. " 12/01/2011 - "PGL-I itself or in the form of semisynthetic neoglycoproteins containing the synthetic terminal disaccharide or the whole trisaccharide chemically conjugated to such as bovine or human serum albumin, has found its greatest utility in the serological diagnosis, confirmation and management of lepromatous leprosy. "
2.	Virus Diseases (Viral Diseases) 02/24/2014 - "Assessment of cytopathic effect showed that the Neu5Gc-capped trisaccharides inhibited the viral infection better than their Neu5Ac counterparts. " 12/01/2005 - "Testing of protective efficacy of the polyacrylamide conjugate bearing Neu5Acalpha2-6Galbeta1-4GlcNAc trisaccharide under conditions of lethal or sublethal virus infection demonstrated a strong protective effect of this preparation. "
3.	Acquired Immunodeficiency Syndrome (AIDS) 09/28/2012 - "A β-mannan trisaccharide conjugate vaccine aids clearance of Candida albicans in immunocompromised rabbits."
4.	Schistosomiasis (Bilharziasis) 03/01/2000 - "Based on the structural relatedness of the cross-reactive fucosyllactose determinant to the antigenic mammalian blood group H trisaccharide, our observations may have implications in serodiagnosis and immunoprophylaxis of schistosomiasis/fascioliasis." 08/01/2009 - "Here we show that monoclonal antibody 54-5C10-A, which is used to diagnose schistosomiasis in humans, interacts with oligomers of at least three Lewis X trisaccharides, but not with monomeric Lewis X. We describe the sequence and the 2.5 A crystal structure of its Fab fragment and infer a possible mode of binding of the polymeric Lewis X from docking studies. "
5.	Polyneuropathies (Polyneuropathy) 06/01/2002 - "Several polyneuropathy syndromes have been described with polyclonal serum immunoglobulin G (IgG) or immunoglobulin M (IgM) binding to gangliosides GM2 and GalNAc-GD1a that contain the terminal trisaccharide moiety GalNAc(beta1-4)Gal(alpha2-3)NeuAc. " 01/01/2017 - "In this study we focused our attention on the trisaccharide human natural killer cell-1 (HNK-1), considered the antigenic determinant of myelin-associated glycoprotein and the target of clinically relevant auto-antibodies in autoimmune neurological disorders such as IgM monoclonal gammopathy and demyelinating polyneuropathy. "

Related Drugs and Biologics

1.	Immunoglobulin M (IgM)
2.	Antibodies
3.	Conjugate Vaccines
4.	Mannans
5.	polyacrylamide
6.	Epitopes
7.	Monoclonal Antibodies
8.	Shiga Toxins (Vero Toxin)
9.	Myelin-Associated Glycoprotein
10.	Immunoglobulin Fab Fragments

Related Therapies and Procedures

1.	Therapeutics