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Digoxigenin

3 beta,12 beta,14-Trihydroxy-5 beta-card-20(22)-enolide. A cardenolide which is the aglycon of digoxin. Can be obtained by hydrolysis of digoxin or from Digitalis orientalis L. and Digitalis lanata Ehrh.
Also Known As:
Lanadigenin; Card-20(22)-enolide, 3,12,14-trihydroxy-, (3beta,5beta,12beta)-
Networked: 331 relevant articles (1 outcomes, 20 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Chae, C: 7 articles (12/2003 - 11/2000)
2. Junker, Kerstin: 3 articles (06/2010 - 03/2002)
3. Woo, Tsung-Ung W: 3 articles (02/2010 - 11/2007)
4. Cho, W S: 3 articles (12/2003 - 01/2002)
5. Boström, Pia: 2 articles (01/2013 - 01/2013)
6. Sainio, Annele: 2 articles (01/2013 - 01/2013)
7. Järveläinen, Hannu: 2 articles (01/2013 - 01/2013)
8. Tanikawa, T: 2 articles (12/2011 - 07/2005)
9. Imai, Y: 2 articles (12/2011 - 07/2005)
10. Kurohane, K: 2 articles (12/2011 - 07/2005)

Related Diseases

1. Infection
2. Carcinoma (Carcinomatosis)
05/01/1997 - "Fine-needle aspirates from 51 breast carcinomas were investigated immunocytochemically for ER/PgR and by in situ hybridization technique using digoxigenin-labeled alpha-satellite probe for chromosome 6. Cases with > or = 70% two-signal nuclei were regarded as disome; the remaining tumors showed aneusomy with a variable number of signals. "
08/01/1996 - "We examined apoptosis in 33 gastric carcinomas using the terminal deoxynucleotydil transferase mediated dUTP-digoxigenin nick end labelling technique (TUNEL). "
10/01/1990 - "Digoxigenin labelled probes proved two to 10-fold more sensitive by quantitative dot blotting and four-fold more sensitive in detecting HPV 16 DNA in a series of 31 anal carcinomas, compared with biotinylated probes. "
03/15/2000 - "We evaluated CRBP expression by in situ hybridization in six reduction mammoplasty specimens and 49 human breast carcinoma specimens by use of digoxigenin-labeled RNA probes and in nine cultured mammoplasty specimens by northern or western blot analysis. "
03/01/2000 - "The aims of this study were to analyze (a) the spontaneous apoptosis in human pancreatic duct carcinoma by terminal deoxynucleotidyl transferase (TdT)-mediated dUTP-digoxigenin nick end labeling (TUNEL); (b) its correlation with the proliferation rate of the tumor (determined by immunohistochemistry by using monoclonal antibody MIB-1); and (c) the association of apoptotic and mitotic index with the histologic features of the tumor and the outcome of patients. "
3. Adenocarcinoma
4. Adenoma (Adenomas)
5. Atherosclerotic Plaque (Atheroma)

Related Drugs and Biologics

1. DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)
2. Messenger RNA (mRNA)
3. DNA (Deoxyribonucleic Acid)
4. Complementary DNA (cDNA)
5. Oligonucleotide Probes
6. Paraffin
7. Formaldehyde (Formol)
8. Complementary RNA (cRNA)
9. Antibodies
10. Antigens

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Ligation
3. Catheters
4. Mammaplasty (Breast Reconstruction)
5. Cystectomy