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Bongkrekic Acid

An antibiotic produced by Pseudomonas cocovenenans. It is an inhibitor of MITOCHONDRIAL ADP, ATP TRANSLOCASES. Specifically, it blocks adenine nucleotide efflux from mitochondria by enhancing membrane binding.
Also Known As:
Bongkrekate; Flavotoxin A; 2,4,8,10,14,18,20-Docosaheptaenedioic acid, 20-(carboxymethyl)-6-methoxy-2,5,17-trimethyl-, (R-(R*,S*-(E,Z,Z,E,E,Z,E)))-
Networked: 18 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Wu, Jen-Leih: 2 articles (02/2010 - 04/2006)
2. Her, Guor Mour: 2 articles (02/2010 - 04/2006)
3. Hong, Jiann-Ruey: 2 articles (02/2010 - 04/2006)
4. Dickenson, John M: 1 article (05/2012)
5. Galiñanes, Manuel: 1 article (05/2012)
6. Husainy, Mohammad Ali: 1 article (05/2012)
7. Chen, Po-Chun: 1 article (02/2010)
8. Castilho, Roger F: 1 article (08/2008)
9. Vercesi, Aníbal E: 1 article (08/2008)
10. Alberici, Luciane C: 1 article (08/2008)

Related Diseases

1. Ischemia
2. Necrosis
3. Foodborne Diseases
4. Blister (Bulla)
5. B-Cell Leukemia (Leukemia, B Cell)

Related Drugs and Biologics

1. Cyclosporine (Ciclosporin)
2. 1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)
3. ATP Translocases Mitochondrial ADP
4. mitochondrial permeability transition pore
5. Caspase 9
6. Caspase 3 (Caspase-3)
7. Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)
8. bcl-2-Associated X Protein (bcl 2 Associated X Protein)
9. Cytochromes c (Cytochrome c)
10. Calcineurin