Photothermal Therapy

Application of LOCAL HYPERTHERMIA within a specific tissue using electromagnetic radiation to convert light/laser into heat often coupled with PHOTOSENSITIZER including nanoparticle.

Also Known As:

Networked: 4097 relevant articles (350 outcomes, 339 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Liu, Zhuang: 52 articles (02/2022 - 09/2010)
2.	Chen, Xiaoyuan: 30 articles (12/2019 - 05/2013)
3.	Wang, Jing: 29 articles (03/2022 - 01/2012)
4.	Liu, Jie: 29 articles (02/2022 - 02/2015)
5.	Huang, Wei: 28 articles (02/2022 - 10/2017)
6.	Zhang, Wei: 27 articles (06/2022 - 03/2017)
7.	Huang, Peng: 25 articles (05/2022 - 02/2010)
8.	Yang, Kai: 25 articles (03/2022 - 09/2010)
9.	Cheng, Liang: 25 articles (02/2022 - 06/2012)
10.	Chen, Wei R: 24 articles (01/2022 - 07/2005)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2023 - "In vitro and in vivo studies demonstrate that the synergistic photodynamic/gas/photothermal therapy triggered by single 660 nm light irradiation is highly effective for tumor treatments." 02/01/2017 - "Both in vitro and in vivo studies indicate that the light-triggered cross-linking can dramatically shift the surface plasmon resonance of Au nanoparticles to near-infrared regions, which in consequence remarkably enhances their efficacy for photothermal therapy and photoacoustic imaging of tumors in vivo." 10/30/2023 - "Targeting and uptake are the most important strategies for enhancing the efficacy of cancer photothermal therapy (PTT) and reducing damage to surrounding normal tissues. " 09/21/2023 - "Photothermal therapy (PTT) is a highly clinical application promising cancer treatment strategy with safe, convenient surgical procedures and excellent therapeutic efficacy on superficial tumors. " 11/17/2021 - "These results suggest that photothermal therapy using aAuYSs is highly effective in the treatment of drug-resistant cancers."
2.	Breast Neoplasms (Breast Cancer) 12/01/2023 - "Collectively, our study provides compelling evidence for the remarkable efficacy of targeted and synergistic chemo-photothermal therapy utilizing all-in-one nanoparticles as a delivery system for BP and chemotherapeutic drug in HER2-positive breast cancer." 01/01/2019 - "In vitro studies indicated that the light-triggered assembling shifted the surface plasmon resonance of AuNPs significantly to near-infrared (NIR) regions, which as a consequence effectively enhanced the efficacy of photothermal therapy for 4T1 breast cancer cells. " 05/30/2019 - "In an effort to develop a photothermal agent with high efficacy for photothermal therapy, we found that (NH4)xWO3 nanorods of length 0.5-1.0 μm and diameter ∼100 nm could destroy breast cancer cells rapidly when irradiated with a wavelength in the therapeutic window. " 10/05/2018 - "Upon near-infrared laser irradiation, the nanocomplexes showed high photothermal therapy and chemotherapeutic efficacy for breast cancer in vivo. " 07/01/2020 - "Thus NioIR-C can be a promising nanosystem for effective treatment of breast cancer using photothermal therapy."
3.	Hyperthermia 02/01/2023 - "We observed that hyperthermia-based photothermal therapy is more effective than ROS-based photodynamic therapy in killing multi-drug resistant bacteria. " 10/12/2022 - "Moreover, under near-infrared light irradiation, the bimetallic nanoparticles display a photothermal conversion efficacy of 46.7%, which not only improves chemodynamic therapy via boosting a Fenton-like reaction but results in photothermal therapy through hyperthermia. " 08/03/2023 - "The O-BT NPs possessed a high extinction coefficient, excellent hyperthermia generation ability, satisfactory NIR-II fluorescence emission, and good batch-to-batch reproducibility, and could be used as high-efficiency phototheranostics for photothermal therapy and NIR-II fluorescence imaging." 06/20/2023 - "Within all strategies, the so-called photothermal therapy proposes to induce the hyperthermia by the remote laser radiation on a photothermal conversion agent, in contact with the target tissue. " 01/05/2023 - "The traditional antibacterial photothermal therapy always results in localized hyperthermia (over 50 °C), which inevitably delays tissue recovery. "
4.	Neoplasm Metastasis (Metastasis) 01/01/2023 - "In this study, a multifunctional nanoplatform is expected to mediate chemo-photothermal therapy, which can combine immunogenic cell death with checkpoint blockade to combat TNBC and distant metastasis. " 01/01/2023 - "Multifunctional IDNPs were successfully synthesized to mediate chemo-photothermal therapy, which combines immunogenic cell death with checkpoint blockade to combat TNBC and distant metastasis, showing great promise preclinically and clinically." 01/01/2022 - "Thus, this review discusses the recent developments in nanotechnology-based photothermal therapy for the treatment of BC and its metastasis to provide potential strategies for future BC treatment." 12/01/2018 - "Photodynamic therapy and photothermal therapy for the treatment of peritoneal metastasis: a systematic review." 10/21/2016 - "A therapeutic strategy that can eliminate primary tumours, inhibit metastases, and prevent tumour relapses is developed herein by combining adjuvant nanoparticle-based photothermal therapy with checkpoint-blockade immunotherapy. "
5.	Melanoma (Melanoma, Malignant) 10/01/2023 - "Notably, the DOX-ICG-cubo exhibited enhanced drug permeation efficiency, good biocompatibility, and improved in vivo anti-melanoma efficacy through the synergistic effects of chemo-photothermal therapy. " 03/01/2022 - "CD137 agonist potentiates the abscopal efficacy of nanoparticle-based photothermal therapy for melanoma." 09/01/2021 - "The aim of this study was to develop a GNR-based targeted photothermal therapy for melanoma. " 01/01/2019 - "Conclusion: Our study describes a convenient method to synthesize a new type of superparamagnetic upconversion nanoprobes, which possess high biocompatibility and can be used in imaging-guided photothermal therapy for the treatment of malignant melanoma. " 10/24/2023 - "Successful fabrication of multifunctional patches with heterogeneously integrated microneedles allows the treatment of melanoma via synergistic photothermal therapy and combination chemotherapy. "

Related Drugs and Biologics

1.	1-phenyl-3,3-dimethyltriazene (PDT)
2.	Gold
3.	Therapeutic Uses
4.	Doxorubicin (Adriamycin)
5.	Photosensitizing Agents (Photosensitizers)
6.	cupric sulfide (CuS)
7.	Silicon Dioxide (Silica)
8.	Ions
9.	Polymers
10.	Oxygen (Dioxygen)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Therapeutics
3.	Photochemotherapy (Photodynamic Therapy)
4.	Lasers (Laser)
5.	Precision Medicine