HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

protopanaxtriol

a cardioprotective agent isolated from Panax notoginseng; structure in first source

Also Known As:

20(S)-protopanaxtriol

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - protopanaxtriol: 3

Experts

1.	Eun, Su-Hyeon: 1 article (09/2015)
2.	Jeong, Jin-Ju: 1 article (09/2015)
3.	Kim, Dong-Hyun: 1 article (09/2015)
4.	Lee, Sang-Yun: 1 article (09/2015)
5.	Chen, Nai-hong: 1 article (03/2015)
6.	Chu, Shi-feng: 1 article (03/2015)
7.	Gao, Yan: 1 article (03/2015)
8.	Guo, Xiao-feng: 1 article (03/2015)
9.	He, Wen-bin: 1 article (03/2015)
10.	Li, Jian-ping: 1 article (03/2015)

Related Diseases

1.	Myocarditis (Carditis) 01/01/2012 - "Then, we examined the protective effects of 20(S)-protopanaxtriol on CVB3-induced myocarditis in BALB/c mice. " 01/01/2012 - "Protective effects of 20(s)-protopanaxtriol on viral myocarditis infected by coxsackievirus B3." 01/01/2012 - "These data provide the possibility that 20(S)-protopanaxtriol can be used as a potential therapeutic means for treatment of viral myocarditis."
2.	Huntington Disease (Huntington's Disease) 03/01/2015 - "Protopanaxtriol protects against 3-nitropropionic acid-induced oxidative stress in a rat model of Huntington's disease."
3.	Heart Diseases (Heart Disease) 01/01/2012 - "20(S)-Protopanaxtriol is a major component of Panax pseudoginseng and has been clinically used for the treatment of heart diseases. "
4.	Colitis 09/05/2015 - "These findings suggest that ginsenoside Rg1 is metabolized to 20(S)-protopanaxtriol via ginsenosides Rh1 and F1 and these metabolites particularly 20(S)-protopanaxtriol, may ameliorate inflammatory disease such as colitis by inhibiting the binding of LPS to TLR4 on macrophages and restoring the Th17/Treg imbalance. " 09/05/2015 - "Orally administered ginsenoside Rg1, Rh1, or 20(S)-protopanaxtriol inhibited 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colon shortening, myeloperoxidase activity, and expression of IL-1β, IL-17, and tumor necrosis factor-α in mice with TNBS-induced colitis. "

Related Drugs and Biologics

1.	Ginsenosides
2.	Interleukin-17 (Interleukin 17)
3.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
4.	Sulfonic Acids
5.	Peroxidase (Myeloperoxidase)
6.	ginsenoside Rg1
7.	sym-trinitrobenzene
8.	3-nitropropionic acid