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6-(nitrooxy)hexyl 2-(6-methoxynaphthalen-2-yl)propanoate

a naproxen prodrug

Also Known As:

NCX 429

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Amoruso, Angela: 1 article (04/2015)
2.	Bardelli, Claudio: 1 article (04/2015)
3.	Brunelleschi, Sandra: 1 article (04/2015)
4.	Dalli, Jesmond: 1 article (04/2015)
5.	Federici Canova, Donata: 1 article (04/2015)
6.	Fresu, Luigia Grazia: 1 article (04/2015)
7.	Miglietta, Daniela: 1 article (04/2015)
8.	Perretti, Mauro: 1 article (04/2015)
9.	Blackler, Rory: 1 article (01/2012)
10.	Bolla, Manlio: 1 article (01/2012)

Related Diseases

1.	Peritonitis 04/01/2015 - "These results demonstrate that both in vitro and in vivo--in a murine model of peritonitis--NCX 429 elicits significant anti-inflammatory activity, beyond the simple COX inhibition or pure NO release. " 04/01/2015 - "Moreover, we compared the in vivo efficacy of NCX 429 and naproxen in a murine model of peritonitis. "
2.	Inflammation (Inflammations) 01/01/2012 - "In contrast, ATB-346 and NCX 429, when tested at doses that were as effective as naproxen and celecoxib in reducing inflammation and inhibiting cyclooxygenase activity, did not produce significant gastric or intestinal damage in any of the models. "

Related Drugs and Biologics

1.	Naproxen (Naprosyn)
2.	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
3.	Celecoxib (Celebrex)
4.	2-(6-methoxy-napthalen-2-yl)-propionic acid 4-thiocarbamoyl-phenyl ester