pregnane glycoside

isolated from the seeds of Digitalis ciliata; structure in first source

Networked: 10 relevant articles (1 outcomes, 0 trials/studies)

1.	Hyperglycemia 05/25/2016 - "Russelioside B, a pregnane glycoside ameliorates hyperglycemia in streptozotocin induced diabetic rats by regulating key enzymes of glucose metabolism."
2.	Body Weight (Weight, Body) 09/01/2013 - "Appetite suppressant effect and body weight loss were observed when tested with the most abundant pregnane glycoside, wilfoside K1N, in an in vivo test with rats. " 02/27/2013 - "Here, we show that pregnane glycoside-enriched extracts from swamp milkweed Asclepias incarnata at 25-100 mg/kg daily attenuated food intake (up to 47.1 ± 8.5% less than controls) and body weight gain in rats (10% for males and 9% for females, respectively) by activating melanocortin signaling and inhibiting gastric emptying. "
3.	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 06/17/2013 - "volubilis(L.f) (Stapf.) sapogenin glycosides mixture (WVSM) and polyhydroxy pregnane glycoside (PPG) isolated from it on neuroprotection and the potential mechanisms in the rat I/R model induced by middle cerebral artery occlusion (MCAO). "
4.	Weight Gain 01/01/2018 - "Pharmacological Action of a Pregnane Glycoside, Russelioside B, in Dietary Obese Rats: Impact on Weight Gain and Energy Expenditure."
5.	Stomach Ulcer (Gastric Ulcer) 01/01/2021 - "Russelioside B; A pregnane glycoside for treatment of gastric ulcer via modulation of heat shock protein-70 and vascular endothelial growth factor."

1.	Streptozocin (Streptozotocin)
2.	Glucose (Dextrose)
3.	Enzymes
4.	Melanocortins
5.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
6.	Cytokines
7.	Glycosides
8.	Concanavalin A
9.	Appetite Depressants (Anorectics)
10.	periplocoside A