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poly(diethylene glycol-l-lysine)-poly(l-lysine)

structure in first source

Also Known As:

PEGLL-PLL

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675

Experts

1.	Atmaja, Bayu: 1 article (12/2010)
2.	Beck, Stayce E: 1 article (12/2010)
3.	Cochran, Jennifer R: 1 article (12/2010)
4.	Frank, Curtis W: 1 article (12/2010)
5.	Hu, Yuhua: 1 article (12/2010)
6.	Lui, Bertrand H: 1 article (12/2010)

Related Diseases

1.	Neoplasms (Cancer) 12/08/2010 - "The assemblies are formed through the self-assembly of carboxyl-functionalized QDs and poly(diethylene glycol-L-lysine)-poly(L-lysine) (PEGLL-PLL) diblock copolypeptide molecules, and they are modified with peptide ligands containing a cyclic arginine-glycine-aspartate [c(RGD)] motif that has affinity for αvβ3 and αvβ5 integrins overexpressed on the tumor vasculature. "
2.	Glioblastoma (Glioblastoma Multiforme) 12/08/2010 - "To illustrate the tunability of the QD-polypeptide assembly system, we show that binding to U87MG glioblastoma cells can be modulated and optimized by changing either the conditions under which the assemblies are formed or the relative lengths of the PEGLL and PLL blocks in the PEGLL-PLL molecules. "

Related Drugs and Biologics

1.	poly(diethylene glycol-l-lysine)-poly(l-lysine)
2.	Integrins
3.	Peptides (Polypeptides)
4.	Ligands
5.	Glycine (Aminoacetic Acid)
6.	Aspartic Acid (Aspartate)
7.	Arginine (L-Arginine)