Glycine (Aminoacetic Acid)

2907  relevant articles (127 outcomes, 291 trials/studies) found for this Drug

Aminoacetic Acid; Glycine Carbonate (1:1), Monosodium Salt; Glycine Carbonate (2:1), Monolithium Salt; Glycine Carbonate (2:1), Monopotassium Salt; Glycine Carbonate (2:1), Monosodium Salt; Glycine Hydrochloride; Glycine Hydrochloride (2:1); Glycine Phosphate; Glycine Phosphate (1:1); Glycine Sulfate (3:1); Glycine, Calcium Salt; Glycine, Calcium Salt (2:1); Glycine, Cobalt Salt; Glycine, Copper Salt; Glycine, Monoammonium Salt; Glycine, Monopotasssium Salt; Glycine, Monosodium Salt; Glycine, Sodium Hydrogen Carbonate; Acid, Aminoacetic; Calcium Salt Glycine; Cobalt Salt Glycine; Copper Salt Glycine; Hydrochloride, Glycine; Monoammonium Salt Glycine; Monopotasssium Salt Glycine; Monosodium Salt Glycine; Phosphate, Glycine; Salt Glycine, Monoammonium; Salt Glycine, Monosodium; 2-aminoacetic acid

Relationship Network

Drug Context: Research Results

Experts

1.	Javitt, Daniel C: 7 articles (01/2008 - 07/2002)
2.	Heresco-Levy, Uriel: 5 articles (03/2007 - 01/2004)
3.	Ogawa, Yoshihide: 4 articles (09/2008 - 09/2003)
4.	Nishijima, Saori: 4 articles (09/2008 - 09/2003)
5.	Miyazato, Minoru: 4 articles (09/2008 - 09/2003)
6.	Sugaya, Kimio: 4 articles (09/2008 - 09/2003)
7.	Ikejima, Kenichi: 3 articles (06/2007 - 09/2003)
8.	Sato, Nobuhiro: 3 articles (06/2007 - 09/2003)
9.	Ermilov, Marina: 3 articles (03/2007 - 01/2004)
10.	Wang, Gang: 3 articles (03/2006 - 03/2004)

Related Diseases

1.	Schizophrenia (Dementia Praecox) 01/01/1999 - "Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia." 01/01/1997 - "At concentrations relevant to its behavioral actions, GDA significantly inhibits forebrain glycine uptake, indicating that glycine uptake inhibition may provide effective treatment for PCP psychosis and PCP psychosis-like symptoms of schizophrenia." 02/01/2008 - "Since the NMDAR complex consists of multiple sites modulating receptor functions, the efficacy of glycine site potentiators for schizophrenia suggests the possibility that manipulation of other modulating sites of the NMDAR can also be efficacious in the treatment of schizophrenia." 08/30/2009 - "Prior studies in schizophrenia subjects documented clinical improvements after 2 weeks of oral glycine administration, suggesting that brain glycine levels are sufficiently elevated to evoke a clinical response within that time frame. " 02/01/2008 - "Consistent with this theory, for the last decade, clinical trials have demonstrated that the enhancement of NMDAR function by potentiating the glycine site of the receptor is efficacious in the treatment of schizophrenia. " Order ALL the reference details at left...
2.	Ischemia 05/15/1995 - "A significant reduction in [3H]glycine binding was found in the hippocampus and thalamus from as early as 1 h after ischemia. " 01/01/2006 - "The aim of this study was to determine whether glycine decreases IRI after warm hepatic ischemia. " 03/01/2002 - "The purpose of this study was to investigate whether a bolus injection of glycine given before reperfusion plus continuous dietary supplementation afterward would reduce renal injury caused by ischemia-reperfusion. " 08/01/2001 - "The goal of this study was to investigate whether prefeeding of glycine reduces the immunoinflammatory response, the degree of distant organ injury (liver), and/or the mortality rate in a two-hit model using intestinal ischemia/reperfusion and endotoxin (ET) challenge 6 h later in rats. " 06/01/1997 - "Diffusion mapping disclosed a delayed treatment effect of this glycine antagonist in focal ischemia, confirmed by the postmortem study." Order ALL the reference details at left...
3.	Reperfusion Injury 01/01/1997 - "These data suggest that enteral glycine supplementation may be beneficial in attenuating intestinal ischemia/reperfusion injury and its related systemic effects in this murine model." 08/15/2009 - "To develop new therapeutic agents against renal ischemia/reperfusion injury, we sought to link an antioxidant moiety (nitronyl nitroxide) to glycine in the hope that the resulting glycine-nitronyl nitroxide conjugate (GNN) would provide a synergetic protection against renal ischemia/reperfusion injury. " 11/01/1991 - "Protective effects of glycine during hypothermic renal ischemia-reperfusion injury." 03/15/2003 - "Glycine ameliorates lung reperfusion injury after cold preservation in an ex vivo rat lung model." 03/01/2001 - "These results indicate that some of the indicators of ischemic-reperfusion injury are improved by pretreatment with a 20% glycine solution." Order ALL the reference details at left...
4.	Seizures (Seizure) 02/01/1989 - "After cerebrospinal fluid glycine levels were normalized, the seizures stopped completely in one child and were markedly improved in the other. " 05/01/1983 - "Assuming the recorded pathways were representative of all glycine-mediated spinal pathways, the results suggested that postsynaptic inhibition could be virtually eliminated before intrinsic spinal seizures were triggered. " 05/01/1999 - "Recently, studies have shown that N-(benzyloxycarbonyl)glycine (Z-glycine) antagonized seizures more than glycine in addition to possessing activity in the maximal electroshock test, a convulsive model in which glycine is inactive. " 01/01/1998 - "Recently, studies have demonstrated that N-(benzyloxycarbonyl)glycine (1) antagonized seizures superior to glycine in addition to activity in the maximal electroshock (MES) test, a convulsive model where glycine is inactive. " 05/01/2007 - "Glycine encephalopathy is typically manifested by refractory neonatal seizures secondary to a defect of the glycine degradative pathway. " Order ALL the reference details at left...
5.	Anoxia (Hypoxia) 10/01/2005 - "CONCLUSION: Glycine might be beneficial in the protection of myocardial cells against hypoxia. " 10/01/1997 - "After the transmembrane electrolyte concentration gradient was eliminated by a "intracellular" buffer or by permeabilizing the plasma membrane to molecules <4 kDa using alpha-toxin, anoxia still caused further membrane disruption that was prevented by glycine or low pH. These results demonstrate that 1) water or net electrolyte influxes are probably not a primary cause for anoxia-induced membrane disruption and 2) glycine could prevent the plasma membrane disruption during anoxia independently from its effect on transmembrane electrolyte or water influxes. " 04/01/1997 - "The aim of this study was to investigate the mechanism of cytoprotection by glycine against hypoxia-induced hepatocellular injury. " 05/01/2007 - "Glycine also drastically decreases changes in the tissue ultrastructure, particularly of mitochondria, arising under anoxia. " 04/01/2007 - "RESULTS: Glycine significantly reduced Na+ overload and hepatocyte death caused by hypoxia. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	N-Methylaspartate (NMDA)
2.	Serine (L-Serine)
3.	Glutamic Acid (Glutamate)
4.	Arginine (L-Arginine)
5.	Amino Acids
6.	Alanine (L-Alanine)
7.	Taurine
8.	Methionine (L-Methionine)
9.	Cycloserine (Seromycin)
10.	GV 150526A

Related Therapies and Procedures

1.	Fluid Therapy (Oral Rehydration Therapy)
2.	Intravenous Injections
3.	Transplantation (Transplant Recipients)
4.	Transplants (Transplant)
5.	Drug Therapy (Chemotherapy)