biotin transporter

a plasma membrane H+-biotin symporter/transporter; RefSeq NM_130746 (rat); NM_021095 (human)

Also Known As:

SLC5A6 protein, human; SMVT protein, human; SMVT protein, rat; SMVT, human; SPAC1B3.16c protein, S pombe; Slc5a6 protein, rat; VHT1 protein, S cerevisiae; YGR065C protein, S cerevisiae; biotin symporter; small intestinal biotin transporter protein, rat; sodium-dependent multivitamin transporter protein, human; sodium-dependent multivitamin transporter, human; sodium-dependent vitamin transporter protein, human; sodium-dependent vitamin transporter protein, rat; solute carrier family 5 (sodium-dependent vitamin transporter), member 6 protein, human; solute carrier family 5, member 6 protein, rat; vht1 protein, S pombe; vitamin H transporter 1 protein, S cerevisiae; vitamin H transporter 1 protein, S pombe

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - Membrane Transport Proteins: 589
      - Ion Pumps: 61
        Symporters: 1442
        biotin transporter: 5
  - Membrane Proteins: 10078
    - Membrane Transport Proteins: 589
      - Ion Pumps: 61
        Symporters: 1442
        biotin transporter: 5

Experts

1.	Neophytou, Constantina: 1 article (01/2022)
2.	Pitsouli, Chrysoula: 1 article (01/2022)
3.	Jon, Sangyong: 1 article (06/2018)
4.	Lee, Soyoung: 1 article (06/2018)
5.	Lee, Yonghyun: 1 article (06/2018)
6.	Mock, Donald M: 1 article (01/2005)
7.	Mock, Nell I: 1 article (01/2005)
8.	Stratton, Shawna L: 1 article (01/2005)
9.	Vlasova, Tatyana I: 1 article (01/2005)
10.	Wells, Amanda M: 1 article (01/2005)

Related Diseases

1.	Carcinogenesis 01/01/2022 - "Here, we study the role of the Drosophila intestinal stem cell (ISC)-specific biotin transporter Smvt in midgut homeostasis, infection-induced regeneration, and tumorigenesis. "
2.	Infections 01/01/2022 - "Here, we study the role of the Drosophila intestinal stem cell (ISC)-specific biotin transporter Smvt in midgut homeostasis, infection-induced regeneration, and tumorigenesis. "
3.	Biotin deficiency 01/01/2005 - "Biotin deficiency reduces expression of SLC19A3, a potential biotin transporter, in leukocytes from human blood." 05/01/2002 - "Cells responded to biotin deficiency with increased expression of biotin transporter genes. " 01/04/2023 - "We previously reported that biotin deficiency (BD) in mice, whether modeled through intestine-specific deletion of biotin transporter (SMVT-icKO) or through a biotin-deficient diet, resulted in intestinal inflammation consistent with an IBD-like phenotype. "
4.	Neoplasms (Cancer) 06/01/2018 - "Tumor targeting is achieved using biotin as a ligand for "biotin transporter"-overexpressing malignant tumors, and bilirubin-based nanoparticles (BRNPs) are used as a drug-delivery carrier that enables ROS-responsive drug release. "
5.	Inflammation (Inflammations) 01/04/2023 - "We previously reported that biotin deficiency (BD) in mice, whether modeled through intestine-specific deletion of biotin transporter (SMVT-icKO) or through a biotin-deficient diet, resulted in intestinal inflammation consistent with an IBD-like phenotype. "

Related Drugs and Biologics

1.	Biotin (Vitamin H)
2.	Ligands
3.	Bilirubin