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3- (4- (4- chlorophenyl- 4- hydroxypiperidino)methyl)indole

structure in first source

Also Known As:

L 741,626; L 741626; L-741,626; L-741626

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - 3-(4-(4-chlorophenyl-4-hydroxypiperidino)methyl)indole: 5
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - 3-(4-(4-chlorophenyl-4-hydroxypiperidino)methyl)indole: 5

Experts

1.	García-Domingo, Mónica: 1 article (12/2020)
2.	García-Pedraza, José Ángel: 1 article (12/2020)
3.	Martín, María Luisa: 1 article (12/2020)
4.	Morán, Asunción: 1 article (12/2020)
5.	Ollauri-Ibáñez, Claudia: 1 article (12/2020)
6.	Rodríguez-Barbero, Alicia: 1 article (12/2020)
7.	Villalón, Carlos M: 1 article (12/2020)
8.	Fukui, Arisa: 1 article (01/2018)
9.	Fukushima, Akihiro: 1 article (01/2018)
10.	Maeda, Yasuhiro: 1 article (01/2018)

Related Diseases

1.	Hypothermia 06/01/2003 - "Moreover, the selective D(2) receptor agonist trihydroxy-N-n-propylnoraporphine (TNPA) elicited a robust hypothermia which was prevented by pretreatment with L-741,626 but not by A-437203. " 06/01/2003 - "In contrast, PD 128907-induced hypothermia was antagonized by SCH 23390, a selective D(1) receptor antagonist, and by L-741,626, a selective D(2) receptor antagonist. " 01/01/2018 - "Here we show that the hypothermia evoked by i.c.v.-oseltamivir is inhibited by non-selective dopamine receptor antagonists (sulpiride and haloperidol) and the D2-selective antagonist L-741,626, but not by D1/D5-selective and D3-selective antagonists (SCH-23390 and SB-277011-A, respectively). " 10/01/2001 - "However, the cannabinoid receptor antagonist SR 141716A inhibited oleamide-induced analgesia in the tail-flick assay, the gamma-aminobutyric acid (GABA)A receptor antagonist bicuculline reversed the analgesia and hypothermia, and the dopamine D2 receptor antagonist L 741626 blocked oleamide's locomotor and analgesic actions. "
2.	Hypersensitivity (Allergy) 10/01/2017 - "Pharmacological analysis using specific inhibitors showed that a selective 5-HT2A receptor antagonist, ketanserin, suppressed butyrate-induced visceral hypersensitivity, whereas a selective dopamine D2 receptor antagonist, L-741626, did not. "
3.	Bradycardia 12/01/2020 - "The vago-inhibition induced by quinpirole (which failed to affect the bradycardia to i.v. ACh) was unchanged after i.v. injections of the antagonists L-741,626 (D2; 100 μg/kg) or SB-277011-A (D3; 100 μg/kg), but it was abolished by L-745,870 (D4; 100 μg/kg). "

Related Drugs and Biologics

1.	Dopamine D2 Receptor Antagonists
2.	Cannabinoid Receptor Antagonists
3.	GABA-A Receptor Antagonists
4.	Oseltamivir (Tamiflu)
5.	5-HT2A Serotonin Receptor (5 HT2A Receptor)
6.	Quinpirole
7.	Dopamine Antagonists
8.	Sulpiride (neogama)
9.	Ketanserin
10.	Haloperidol (Haldol)

Related Therapies and Procedures

1.	Injections
2.	Analgesia