Haloperidol (Haldol)

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3552 relevant articles (261 outcomes, 538 trials/studies) found for this Drug

Description: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in MENTAL RETARDATION and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)

Also Known As:

Haldol; 1-Butanone, 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-

Relationship Network

Drug Context: Research Results

Organic Chemicals: 40

Experts

1.	Kulkarni, Shrinivas K: 11 articles (09/2008 - 06/2002)
2.	Lieberman, Jeffrey A: 7 articles (12/2005 - 02/2002)
3.	Volavka, Jan: 7 articles (08/2005 - 02/2002)
4.	Breier, A: 7 articles (11/2003 - 03/2000)
5.	Lindenmayer, Jean-Pierre: 6 articles (03/2007 - 02/2002)
6.	Czobor, Pal: 6 articles (08/2005 - 02/2002)
7.	Sheitman, Brian: 6 articles (07/2005 - 02/2002)
8.	Citrome, Leslie: 6 articles (07/2005 - 02/2002)
9.	Naidu, Pattipati S: 6 articles (09/2003 - 06/2002)
10.	Bishnoi, Mahendra: 5 articles (09/2008 - 01/2007)

Related Diseases

1.	Schizophrenia (Dementia Praecox) 11/05/1997 - "It is as effective as haloperidol against the positive symptoms of schizophrenia, and more effective against negative symptoms, with significantly fewer extrapyramidal side-effects" 07/04/2006 - "Haloperidol is a prototype of typical APDs, and the other three drugs are atypical APDs, which are effective in reducing negative symptoms and cognitive deficits of schizophrenia, cause less side effects, and are more tolerable compared to haloperidol" 08/01/2002 - "Extract of Ginkgo biloba added to haloperidol was effective for positive symptoms in refractory schizophrenia." 12/01/2003 - "haloperidol for reducing the symptoms of acute schizophrenia during the first 24 hours of treatment, the efficacy of both being evident within 2 hours after the first injection" 12/01/1999 - "CONCLUSIONS: EGb may enhance the efficacy of classic antipsychotic haloperidol on schizophrenia, especially on positive symptoms" Order ALL the reference details at left...
2.	Catalepsy 07/11/1985 - "Ablation of the frontal or parietal cortex led to a marked decrease in haloperidol catalepsy, whereas lesions of the occipital cortex, or of the olfactory bulbs did not affect catalepsy, when measured 3 weeks post lesion in all cases" 10/15/2008 - "In addition, compound 35 had good metabolic stability with a scaled intrinsic clearance of 3 mL/min/kg (HLM) and demonstrated efficacy in the haloperidol induced catalepsy model." 01/01/1984 - "Higher doses of haloperidol (1 and 5 mg/kg) produced significantly greater catalepsy in the hyperthyroid rats and significantly reduced catalepsy in the hypothyroid rats" 01/01/1993 - "In contrast, haloperidol was found to be more effective in inducing catalepsy after i.v. (ED50 = 0.4 mumol/kg) than after i.p" 02/01/2008 - "The objective of the study was to evaluate the anticataleptic effect of Withania somnifera (WS) extract, on haloperidol-induced catalepsy in albino mice" Order ALL the reference details at left...
3.	Bipolar Disorder (Mania) 01/01/2006 - "AUTHORS' CONCLUSIONS: There is some evidence that haloperidol is an effective treatment for acute mania" 01/01/2005 - "It is paradoxical to note that, in Europe, haloperidol is still the reference substance used in clinical trials despite the fact that it is not officially indicated in the treatment of mania" 08/01/2001 - "In this study, the authors examined the relationship between steady-state haloperidol blood levels and clinical response in patients with acute psychotic mania" 07/01/2000 - "METHOD: Thirty-one consenting acute inpatient subjects between ages 19 and 66 years with a DSM-III-R clinical diagnosis of bipolar disorder, manic with psychotic features were entered into this double-blind study and were randomly assigned to receive either haloperidol 25 mg/day or haloperidol 5 mg for the 3-week study" 01/01/2006 - "OBJECTIVES: To assess the effects of haloperidol for the treatment of mania in comparison with placebo or other active drugs, either as monotherapy or add-on treatment" Order ALL the reference details at left...
4.	Delirium 01/01/2007 - "Low dose haloperidol may be effective in decreasing the degree and duration of delirium in post-operative patients, compared with placebo" 07/01/1995 - "Experience with continuous haloperidol infusions is growing, and it appears to be an effective method for control of severe agitation or delirium" 03/01/2008 - "Two trials of haloperidol prophylaxis identified reduced severity and duration of delirium in one and reduced incidence in the other" 01/01/2007 - "Low dose haloperidol decreased the severity and duration of delirium in post-operative patients, although not the incidence of delirium, compared to placebo controls in one study" 10/01/2005 - "OBJECTIVES: To study the effectiveness of haloperidol prophylaxis on incidence, severity, and duration of postoperative delirium in elderly hip-surgery patients at risk for delirium" Order ALL the reference details at left...
5.	Syndrome 03/02/1992 - "Haloperidol is commonly considered the most effective in this syndrome." 03/01/2008 - "We report a 94 year-old woman with the characteristic clinical picture of the syndrome that improved with haloperidol." 10/20/1976 - "Untreated patients showed no impairment of temporal processing while those treated with haloperidol showed significant deficit in amount of transmitted information comparable to prior studies of brain syndromes." 01/01/1964 - "CONTRIBUTION TO THE STUDY OF A NEURODYSLEPTIC SYNDROME IN THE COURSE OF HALOPERIDOL THERAPY.]" 12/01/1960 - "The effect of R-1625 (Haloperidol) in mental syndromes: a multiblind study." Order ALL the reference details at left...

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