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TH-DPA

Also Known As:

7S,15R,16S,17S-tetrahydroxy-docosapentaenoic acid

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793

Experts

1.	Choi, Hack Sun: 1 article (02/2022)
2.	Heo, Sun-Yeon: 1 article (02/2022)
3.	Jang, Yong-Suk: 1 article (02/2022)
4.	Ju, Jung-Hyun: 1 article (02/2022)
5.	Oh, Back-Rock: 1 article (02/2022)
6.	Seo, Jeong-Woo: 1 article (02/2022)
7.	Su, Yan: 1 article (02/2022)
8.	Wang, Lifang: 1 article (02/2022)
9.	Yi, Jong-Jae: 1 article (02/2022)

Related Diseases

1.	Obesity 02/15/2022 - "Taken together, our data indicate that diHEP-DPA and TH-DPA ameliorate liver inflammation and inhibit HFD-induced obesity in mice."
2.	Inflammation (Inflammations) 02/15/2022 - "Western blotting and quantitative RT-PCR confirmed that diHEP-DPA or TH-DPA administration modulated the expression of inflammation-related genes (TNF-α and IL-6) and inhibited activation of the NF-κB signaling pathway in livers of HFD-fed mice. " 02/15/2022 - "Taken together, our data indicate that diHEP-DPA and TH-DPA ameliorate liver inflammation and inhibit HFD-induced obesity in mice." 02/15/2022 - "The docosahexaenoic acid derivatives, diHEP-DPA and TH-DPA, synthesized via recombinant lipoxygenase, ameliorate disturbances in lipid metabolism and liver inflammation in high fat diet-fed mice." 02/15/2022 - "Measurements of adipose accumulation and liver inflammation showed that both diHEP-DPA and TH-DPA decreased adipose tissue mass and liver color depth, as well as total cholesterol, triglycerides, and low-density lipoprotein-cholesterol in the serum of HFD-fed mice compared with mice in the HFD-only group, while elevating high-density lipoprotein-cholesterol. "

Related Drugs and Biologics

1.	Triglycerides (Triacylglycerol)
2.	Lipoxygenase (Lipoxygenase-1)
3.	LDL Cholesterol
4.	HDL Cholesterol
5.	Docosahexaenoic Acids
6.	Cholesterol
7.	diHEP-DPA