HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

MRJF22

prodrug of the sigma ligand haloperidol metabolite II conjugated with the histone deacetylase inhibitor valproic acid

Also Known As:

4-((4-chlorophenyl)-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butyl-2-propylpentanoate

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - MRJF22: 1
Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Valerates: 135
      - MRJF22: 1
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Valerates: 135
      - MRJF22: 1

Experts

1.	Amata, Emanuele: 1 article (01/2021)
2.	Anfuso, Carmelina Daniela: 1 article (01/2021)
3.	Barbaraci, Carla: 1 article (01/2021)
4.	Cacciatore, Ivana: 1 article (01/2021)
5.	Dichiara, Maria: 1 article (01/2021)
6.	Giurdanella, Giovanni: 1 article (01/2021)
7.	Leotta, Claudia Giovanna: 1 article (01/2021)
8.	Longo, Anna: 1 article (01/2021)
9.	Lupo, Gabriella: 1 article (01/2021)
10.	Marrazzo, Agostino: 1 article (01/2021)

Related Diseases

1.

01/01/2021 - "Herein, the asymmetric synthesis of (R)-(+)-MRJF22 and (S)-(-)-MRJF22 was performed to investigate their contribution to (±)-MRJF22 antiangiogenic effects in human retinal endothelial cells (HREC) and to assess their therapeutic potential in primary human uveal melanoma (UM) 92-1 cell line. "
01/01/2021 - "Haloperidol Metabolite II Valproate Ester (S)-(-)-MRJF22: Preliminary Studies as a Potential Multifunctional Agent Against Uveal Melanoma."

Related Drugs and Biologics

1.	Valproic Acid (Depakote)
2.	Haloperidol (Haldol)
3.	Esters
4.	Retinaldehyde (Retinal)