HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

(R)-ND-336

Also Known As:

(R)-(4-(4-((Thiiran-2-ylmethyl)sulfonyl)phenoxy)phenyl)methanamine Hydrochloride)

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Methylamines: 15
    - (R)-ND-336: 4
- Sulfur Compounds: 278
  - Sulfides: 1062
    - (R)-ND-336: 4
Inorganic Chemicals: 9
- Electrolytes: 16106
  - Ions: 7857
    - Anions: 3501
      - Sulfides: 1062
        (R)-ND-336: 4
- Sulfur Compounds: 278
  - Hydrogen Sulfide: 2764
    - Sulfides: 1062
      - (R)-ND-336: 4

Experts

1.	Chang, Mayland: 3 articles (01/2022 - 01/2021)
2.	Nguyen, Trung T: 3 articles (01/2022 - 01/2021)
3.	Anderson, Bowen: 2 articles (01/2022 - 02/2021)
4.	Mobashery, Shahriar: 2 articles (01/2022 - 02/2021)
5.	Peng, Zhihong: 2 articles (01/2022 - 02/2021)
6.	Schroeder, Valerie A: 2 articles (01/2022 - 02/2021)
7.	Wolter, William R: 2 articles (01/2022 - 02/2021)
8.	Konai, Mohini Mohan: 1 article (01/2022)
9.	Page-Mayberry, Toni: 1 article (01/2022)
10.	Peterson, Charles E: 1 article (01/2022)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2021 - "(R)-ND-336 accelerated wound healing in diabetic mice by decreasing ROS and NF-κB, lowering inflammation, and increasing angiogenesis. " 02/12/2021 - "We evaluated the efficacy of the selective small-molecule MMP-9 inhibitor, (R)-ND-336, in the infected diabetic mouse model of wound healing and showed that (R)-ND-336 alone or in combination with the antibiotic linezolid improves wound healing by inhibiting the detrimental MMP-9, mitigating macrophage infiltration to diminish inflammation, and increasing angiogenesis to restore the normal wound healing process. "
2.	Rare Diseases (Rare Disease) 08/12/2022 - "(R)-ND-336 holds the promise of a therapeutic recourse for pterygium as an orphan disease."
3.	Wounds and Injuries (Trauma) 01/01/2022 - "In a mouse model of PUs, a highly selective inhibitor for MMP-9 and MMP-14, (R)-ND-336, accelerated wound closure in parallel with significant amelioration of ulcer stage. "
4.	Ulcer 01/01/2022 - "In a mouse model of PUs, a highly selective inhibitor for MMP-9 and MMP-14, (R)-ND-336, accelerated wound closure in parallel with significant amelioration of ulcer stage. "
5.	Suppuration 01/01/2022 - "(R)-ND-336 holds promise as a first-in-class treatment for PUs." 01/01/2022 - "In a mouse model of PUs, a highly selective inhibitor for MMP-9 and MMP-14, (R)-ND-336, accelerated wound closure in parallel with significant amelioration of ulcer stage. "

Related Drugs and Biologics

1.	Anti-Bacterial Agents (Antibiotics)
2.	Linezolid (Zyvox)
3.	Collagen