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2- ((3- (4- tert- butylphenoxy)- 4'- (trifluoromethoxy)(1,1'- biphenyl)- 4- yl)oxy)acetic acid

inhibitor of plasminogen activator inhibitor-1

Also Known As:

IMD-4690

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Biphenyl Compounds: 7
        2-((3-(4-tert-butylphenoxy)-4'-(trifluoromethoxy)(1,1'-biphenyl)-4-yl)oxy)acetic acid: 1
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acetates: 4994
      - 2-((3-(4-tert-butylphenoxy)-4'-(trifluoromethoxy)(1,1'-biphenyl)-4-yl)oxy)acetic acid: 1
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Acetates: 4994
      - 2-((3-(4-tert-butylphenoxy)-4'-(trifluoromethoxy)(1,1'-biphenyl)-4-yl)oxy)acetic acid: 1

Experts

1.	Aono, Yoshinori: 1 article (01/2015)
2.	Azuma, Masahiko: 1 article (01/2015)
3.	Fujikawa, Tomoyuki: 1 article (01/2015)
4.	Goto, Hisatsugu: 1 article (01/2015)
5.	Hanibuchi, Masaki: 1 article (01/2015)
6.	Itai, Akiko: 1 article (01/2015)
7.	Nishioka, Yasuhiko: 1 article (01/2015)
8.	Ogawa, Hirohisa: 1 article (01/2015)
9.	Tezuka, Toshifumi: 1 article (01/2015)
10.	Uehara, Hisanori: 1 article (01/2015)

Related Diseases

1.	Airway Remodeling 01/01/2015 - "IMD-4690, a novel specific inhibitor for plasminogen activator inhibitor-1, reduces allergic airway remodeling in a mouse model of chronic asthma via regulating angiogenesis and remodeling-related mediators." 01/01/2015 - "These results suggest that PAI-1 plays crucial roles in airway inflammation and remodeling, and IMD-4690, a specific PAI-1 inhibitor, may have therapeutic potential for patients with refractory asthma due to airway remodeling. "
2.	Inflammation (Inflammations) 01/01/2015 - "IMD-4690 is a newly synthesized inhibitor for PAI-1, whereas the effect on allergic airway inflammation and remodeling is still unclear. " 01/01/2015 - "These results suggest that PAI-1 plays crucial roles in airway inflammation and remodeling, and IMD-4690, a specific PAI-1 inhibitor, may have therapeutic potential for patients with refractory asthma due to airway remodeling. "
3.	Asthma (Bronchial Asthma) 01/01/2015 - "IMD-4690, a novel specific inhibitor for plasminogen activator inhibitor-1, reduces allergic airway remodeling in a mouse model of chronic asthma via regulating angiogenesis and remodeling-related mediators." 01/01/2015 - "These results suggest that PAI-1 plays crucial roles in airway inflammation and remodeling, and IMD-4690, a specific PAI-1 inhibitor, may have therapeutic potential for patients with refractory asthma due to airway remodeling. "

Related Drugs and Biologics

1.	Plasminogen Activator Inhibitor 1
2.	Plasminogen Activators (Plasminogen Activator)