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methyl-gamma-butyrobetaine

Also Known As:

4-(ethyl(dimethyl)ammonio)butanoate; methyl-GBB

Networked: 5 relevant articles (3 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Dambrova, Maija: 3 articles (08/2017 - 09/2015)
2.	Grinberga, Solveiga: 3 articles (08/2017 - 09/2015)
3.	Kuka, Janis: 3 articles (08/2017 - 09/2015)
4.	Liepinsh, Edgars: 3 articles (08/2017 - 09/2015)
5.	Makrecka-Kuka, Marina: 3 articles (08/2017 - 09/2015)
6.	Sevostjanovs, Eduards: 3 articles (08/2017 - 09/2015)
7.	Cirule, Helena: 2 articles (08/2017 - 09/2015)
8.	Makarova, Elina: 2 articles (11/2016 - 09/2015)
9.	Volska, Kristine: 2 articles (11/2016 - 09/2015)
10.	Svalbe, Baiba: 1 article (11/2016)

Related Diseases

1.	Infarction (Infarctions) 12/01/2023 - "In addition, treatment with methyl-GBB significantly reduced the infarct size and improved neurological outcomes after MCAO. " 03/01/2015 - "In vivo pretreatment with Methyl-GBB (20 mg·kg(-1)) attenuated the infarct size by 45% and improved 24 h survival of rats by 20-30%. " 08/01/2017 - "In conclusion, the anti-infarction effect of methyl-GBB continues for at least 2 weeks post-treatment. " 08/01/2017 - "A significant Pearson correlation (r = 0.48, p = 0.026) was found between infarct size and LCAC tissue content in the methyl-GBB-treated rat hearts. " 08/01/2017 - "Methyl-GBB pre-treatment for 28 days decreased LCAC heart tissue content by 87%, and the infarct size was decreased by 57%. "
2.	Insulin Resistance 11/01/2016 - "Methyl-GBB administration, exercise and the combination of both improved insulin sensitivity and reduced blood glucose levels in db/db mice. " 11/01/2016 - "We used a novel compound, 4-[ethyl(dimethyl)ammonio]butanoate (methyl-GBB), treatment and exercise to decrease acylcarnitine contents in the plasma and muscles in the insulin resistance models of high fat diet (HFD) fed C57BL/6 mice and db/db mice. "
3.	Atherosclerosis 09/01/2015 - "Methyl-GBB administration significantly attenuated the development of atherosclerosis in apoE(-/-)mice. " 09/01/2015 - "In this study, we evaluated the effects of γ-butyrobetaine (GBB), l-carnitine and methyl-GBB administration on the progression of atherosclerosis. "
4.	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 12/01/2023 - "This study aimed to test whether lowering LCAC levels with the anti-ischemia compound 4-[ethyl(dimethyl)ammonio]butanoate (methyl-GBB) protects brain mitochondrial function and improves neurological outcomes after transient middle cerebral artery occlusion (MCAO). "
5.	Ischemia 12/01/2023 - "This study aimed to test whether lowering LCAC levels with the anti-ischemia compound 4-[ethyl(dimethyl)ammonio]butanoate (methyl-GBB) protects brain mitochondrial function and improves neurological outcomes after transient middle cerebral artery occlusion (MCAO). "

Related Drugs and Biologics

1.	Blood Glucose (Blood Sugar)
2.	Carnitine (L-Carnitine)
3.	gamma-butyrobetaine (butyrobetaine)
4.	acylcarnitine
5.	Apolipoproteins E (ApoE)