The use of one gram daily cimetidine in the treatment of peptic ulcer in Singapore.

An open study was conducted to assess the efficacy of Cimetidine one gram daily in the treatment of peptic ulcer amongst outpatients in Singapore. Forty patients with duodenal ulcer and fourteen patients with gastric ulcer were entered into the study. Ulcer healing was assessed by endoscopy. At six weeks 85% of duodenal ulcers and 64% of gastric ulcers healed. Although the study is uncontrolled the figures suggest that Cimetidine I gram daily is effective in the treatment of duodenal ulcer in Singapore outpatients. The efficacy of Cimetidine in gastric ulcer, however requires further study.
AuthorsJ Y Kang, S K Ng, R Guan
JournalAnnals of the Academy of Medicine, Singapore (Ann Acad Med Singapore) Vol. 12 Issue 4 Pg. 545-7 (Oct 1983) ISSN: 0304-4602 [Print] SINGAPORE
PMID6678136 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Trimipramine
  • Cimetidine
  • Adult
  • Aged
  • Cimetidine (administration & dosage, therapeutic use)
  • Drug Evaluation
  • Duodenal Ulcer (complications, drug therapy)
  • Dyspepsia (complications)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Peptic Ulcer Hemorrhage (complications)
  • Singapore
  • Stomach Ulcer (complications, drug therapy)
  • Trimipramine (therapeutic use)

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