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Preparation and Application of High-Efficiency, Antibacterial, and Antiviral PET-PTHP Fibers.

Abstract
Transmission through the respiratory tract is one of the most important ways for bacteria and viruses to infect the human body; the use of high-performance antibacterial and antiviral protective equipment is the most effective way to prevent the spread of respiratory diseases. However, at present, most personal protective equipment lacks the ability to kill pathogens. In this paper, a kind of polytetrahydropyrimidine-polyethylene terephthalate functional fiber (PET-PTHP fibers) with highly sustained antibacterial and antiviral properties was prepared. The inactivation rate of the fibers against Staphylococcus aureus and Escherichia coli was as high as 99.99%, and the antibacterial time was more than 72 h. The fibers have an obvious destructive effect on lentiviruses and can reduce the infection rate of lentiviruses in BxPC-3 cells from 25.4 to 9.7%. The cytotoxicity test, cell live/dead staining test, and cell proliferation test all confirmed that PET-PTHP fibers have no obvious cytotoxicity and good cytocompatibility. By applying the functional fibers to the inner layer of the masks, a new type of mask with adsorption, filtration, and killing properties against pathogens was prepared. The filtration efficiency of the new masks was 99.3%, and the pressure drop was 104 Pa. The new masks have excellent air permeability and filtration effect, meet the practical application conditions, and are of grade A; therefore, these masks provide medical protection as well as kill pathogens at the same time, further reducing the risk of human infection.
AuthorsXiangqiong He, Pengbao Shi, Taixia Wu, Bing Yu, Hailin Cong, Youqing Shen
JournalACS applied materials & interfaces (ACS Appl Mater Interfaces) Vol. 15 Issue 41 Pg. 48660-48672 (Oct 18 2023) ISSN: 1944-8252 [Electronic] United States
PMID37797239 (Publication Type: Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Polyethylene Terephthalates
  • Antiviral Agents
Topics
  • Humans
  • Anti-Bacterial Agents (pharmacology)
  • Polyethylene Terephthalates
  • Personal Protective Equipment
  • Antiviral Agents (pharmacology)

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