Uptake of indium-111-labeled leukocytes by brain metastasis.

Abstract

Uptake of indium-labeled leukocytes was seen in two cases of histologically proven brain metastasis. In one, this led to misdiagnosis of the lesion as an abscess. On histological evaluation, a large number of white blood cells or macrophages was seen at the neoplastic sites. Reasons for leukocyte accumulation around metastatic brain neoplasms are discussed. In contrast to the current reports that indium-labeled leukocyte scans can differentiate intracranial infection from tumor, these cases demonstrate their lack of specificity in the detection of brain abscess.

• Authors: S Balachandran, M M Husain, J R Adametz, J S Pallin, T L Angtuaco, C M Boyd
• Journal: Neurosurgery (Neurosurgery) Vol. 20 Issue 4 Pg. 606-9 (Apr 1987) ISSN: 0148-396X [Print] United States
• PMID: 3587554 (Publication Type: Case Reports, Journal Article)

Chemical References

• Radioisotopes
• Indium

Topics

• Aged
• Aged, 80 and over
• Brain Abscess (diagnostic imaging)
• Brain Neoplasms (diagnostic imaging, pathology, secondary)
• Diagnosis, Differential
• Humans
• Indium
• Leukocytes
• Male
• Middle Aged
• Radiography
• Radioisotopes
• Radionuclide Imaging