Abstract | Background: Methods: After a systematic research, eligible studies (the ones enrolled female patients treated for chronic pelvic pain or for dyspareunia, dysuria, dyschezia, and dysmenorrhea with or without chronic pelvic pain) were assessed at individual patient data level. Conditional probabilities were calculated to assess variables conditioning the rates of good responders ( pain score points more or equal to 3 reduction), poor responders (2 pain score reduction), and nonresponders at a three-month follow-up. Results: Only cases treated with palmitoylethanolamide comicronized with polydatin for a short period can be assessed. Good responders are more than 50%. In chronic pelvic pain, there is a 19.0% conditional probability to find good responders among patients with pain score at enrolment of 6 to 8 and of 6.8% to find poor responders among patients with a pain score at enrolment of 6 to 8. Painful disease does not matter on responders' rates. Conclusion:
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Authors | Ugo Indraccolo, Alessandro Favilli, Arianna Dell'Anna, Antonio Di Francesco, Barbara Dionisi, Emilio Giugliano, Filippo Murina, Erica Stocco |
Journal | BioMed research international
(Biomed Res Int)
Vol. 2022
Pg. 8620077
( 2022)
ISSN: 2314-6141 [Electronic] United States |
PMID | 35578721
(Publication Type: Journal Article, Review)
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Copyright | Copyright © 2022 Ugo Indraccolo et al. |
Chemical References |
- Amides
- Ethanolamines
- Glucosides
- Palmitic Acids
- Stilbenes
- palmidrol
- polydatin
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Topics |
- Amides
- Chronic Pain
(drug therapy)
- Dysmenorrhea
- Endometriosis
- Ethanolamines
(therapeutic use)
- Female
- Glucosides
- Humans
- Palmitic Acids
(therapeutic use)
- Pelvic Pain
(drug therapy)
- Stilbenes
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