Prophylactic antibiotics in transurethral resection of bladder tumors: are they necessary?

Abstract

In a double-blind study, 30 patients having transurethral surgery for bladder tumors were randomly assigned to receive prophylactic carbenicillin indanyl sodium or a placebo perioperatively. Only one patient in the carbenicillin group had a postoperative urinary infection due to carbenicillin-resistant Klebsiella oxytoca organisms. Thus, no advantage from the prophylactic use of antibiotics was evident in this uninfected group of patients.

• Authors: J D Upton, S Das
• Journal: Urology (Urology) Vol. 27 Issue 5 Pg. 421-3 (May 1986) ISSN: 0090-4295 [Print] United States
• PMID: 3518183 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Bacterial Agents
• Placebos
• carbenicillin indanyl
• Carbenicillin

Topics

• Adult
• Aged
• Anti-Bacterial Agents (therapeutic use)
• Carbenicillin (analogs & derivatives, therapeutic use)
• Clinical Trials as Topic
• Double-Blind Method
• Female
• Humans
• Male
• Middle Aged
• Placebos
• Premedication
• Prospective Studies
• Random Allocation
• Urinary Bladder Neoplasms (surgery)
• Urinary Tract Infections (prevention & control)