Abstract | BACKGROUND: METHODS: During the study period, 866 recipients underwent kidney transplant surgery. We studied the distribution of pathogens, resistance rate of MDR bacteria and the risk factors of MDR bacterial infection. RESULTS: Totally, 214 species of pathogens (110 species were MDR bacteria) were isolated in 119 KTR. Escherichia coli (E. coli) was the most common bacteria of the infection. MDR extended spectrum β-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) were most resistant to ampicillin, cefazolin, ciprofloxacin and complex sulfamethoxazole, while quite sensitive to imipenem, amikacin and piperacillin/tazobactam (PIT). All MDR gram-positive bacteria were quite sensitive to linezolid and vancomycin, except that MDR Staphylococcus was also susceptible to rifampicin. Female gender (OR = 3.497, 95% CI = 1.445-8.467, P = 0.006), pathogen types > 1 (OR = 3.832, 95% CI = 1.429-10.273, P = 0.008) and postoperative time < 3 months (OR = 0.331, 95% CI = 0.137-0.799, P = 0.014) were independent risk factors for MDR bacterial infection. CONCLUSION:
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Authors | Liying Gong, Luwei Zhang, Xiaoli Liu, Bekzod Odilov, Shengnan Li, Zhao Hu, Xiaoyan Xiao |
Journal | Infection and drug resistance
(Infect Drug Resist)
Vol. 14
Pg. 5661-5669
( 2021)
ISSN: 1178-6973 [Print] New Zealand |
PMID | 34992392
(Publication Type: Journal Article)
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Copyright | © 2021 Gong et al. |